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Race to unconsciousness: which anesthetic works faster?

NCT ID NCT07717684

Symptom relief Sponsor: Universidade Federal de Sergipe Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 21, 2026 · Last updated Aug 05, 2026 · Updated 3 times

Summary

This trial compares two drugs used to put people to sleep for gallbladder surgery: remimazolam and propofol. Researchers measure how quickly each drug causes loss of consciousness and check for side effects like low blood pressure. Participants are healthy adults aged 18–50 undergoing planned laparoscopic gallbladder removal.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
remimazolam or propofol
What this could lead to
If remimazolam proves faster or safer than propofol, it could become a preferred anesthetic for routine surgeries.
What could go wrong
This is a small, single-center trial in healthy adults, so results may not apply broadly. Both drugs carry risks like low blood pressure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 66 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 49 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 years or older. * American Society of Anesthesiologists (ASA) physical status I or II. * Scheduled to undergo elective laparoscopic cholecystectomy under Total Intravenous Anesthesia (TIVA). Exclusion Criteria: * Patients younger than 18 years or older than 50 years * American Society of Anesthesiologists (ASA) physical status III to V * Body Mass Index (BMI) \< 17.5 kg/m² or \> 30 kg/m² * Hemodynamically unstable patients * Altered or impaired renal or hepatic function * Neuromuscular disorders * History of alcohol or drug dependence * History of allergy or hypersensitivity to any of the anesthetic medications utilized in the protocol

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Conditions

The condition(s) this trial relates to.

cholelithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cholelithiasis Intravenous anesthesia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hospital Univeritário da Universidade Federal de Sergipe

    RECRUITING

    Aracaju, Sergipe, Brazil

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