Choledocholithiasis
MONDO:0006699Presence or formation of gallstones in the common bile duct.
44 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New balloon method may simplify bile duct stone removal during gallbladder surgery
Disease control CompletedThis study tested a technique where a balloon is used to widen the bile duct opening and clear stones during emergency gallbladder removal surgery. 100 adults with bile duct stones took part. After surgery, an MRI scan checked if all stones were gone. The goal was to see if this …
Sponsor: North Estonia Medical Centre • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Stent showdown: double stents may clear tough bile stones in cirrhosis patients
Disease control CompletedThis study looked at 400 people with liver cirrhosis who had large or complex bile duct stones that couldn't be removed during a first procedure. Doctors placed either one or two plastic stents to help drain the bile and make stones easier to remove later. The goal was to find th…
Phase: NA • Sponsor: National Liver Institute, Egypt • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Can a tiny plastic stent keep gallstones away before surgery?
Disease control CompletedThis study looked at whether placing a temporary plastic tube (stent) in the bile duct after removing gallstones helps prevent stones from returning while patients wait for gallbladder surgery. 200 adults with both gallbladder and bile duct stones took part. Half got the stent, h…
Phase: NA • Sponsor: National Liver Institute, Egypt • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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New 'Smart' cut during ERCP aims to slash complication rates
Disease control CompletedThis study tested a new way to open the bile duct during an ERCP procedure. Instead of the standard pull-type cut, doctors used a special hooked knife (ASD) designed to cut only the circular muscle layer, potentially causing less damage. Over 1,500 patients were randomly assigned…
Phase: NA • Sponsor: Military Medical Clinical Center of the Southern Region, Ukraine • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase: PHASE4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New disposable scope cover may lower infection risk in gut procedures
Disease control CompletedThis study tested two types of endoscopes used in ERCP, a procedure to treat bile duct and pancreas problems. One scope had a single-use plastic cover on its tip, while the other was a standard reusable scope. Researchers compared how well each worked and how often complications …
Phase: NA • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 26, 2026 17:07 UTC
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New imaging tool aims to sharpen bile duct diagnosis
Diagnosis CompletedThis completed study tested a device called NvisionVLE® that helps doctors see bile duct details during a procedure called ERCP. Only 3 adults who had the procedure between 2017 and 2019 took part. The goal was to check if the device is safe and can better find abnormalities to g…
Sponsor: Methodist Health System • Aim: Diagnosis
Last updated Jun 27, 2026 12:00 UTC
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Extra fluids during ERCP may prevent pancreatitis, study finds
Prevention CompletedThis study looked at whether giving more IV fluids (aggressive hydration) during an ERCP procedure can prevent pancreatitis, a common complication. 126 adults having their first ERCP were randomly assigned to receive either standard or extra fluids. The goal was to see if extra f…
Phase: NA • Sponsor: Lahore General Hospital • Aim: Prevention
Last updated Jun 27, 2026 09:06 UTC
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Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Battle of the belly buttons: which incision is best for gallbladder surgery?
Knowledge-focused CompletedThis study compared two methods of creating the first opening (pneumoperitoneum) in laparoscopic gallbladder removal: one through the belly button and one just below it. Researchers looked at how fast each method was, complications, pain, hospital stay, and cosmetic satisfaction.…
Phase: NA • Sponsor: Dr Mudassar Saeed Pansota • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Tiny tube tracks bile duct healing after gallstone removal
Knowledge-focused CompletedThis study looked at 13 people aged 15 to 70 who had their gallbladder and bile duct stones removed. Right after surgery, doctors placed a small tube in the bile duct to measure pressure, then checked it weekly for six weeks. The goal was to understand how the bile duct heals and…
Phase: NA • Sponsor: Hospital General de Chihuahua - Dr. Salvador Zubirán Anchondo • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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New study maps antibiotic resistance in bile duct infections to guide smarter treatment
Knowledge-focused CompletedThis study looked at 1435 patients with acute cholangitis (a bile duct infection) who had an ERCP procedure. Researchers analyzed bile samples to understand which bacteria were causing the infections and how resistant they were to antibiotics. The goal was to find patterns that c…
Sponsor: Emergency County Hospital Pius Brinzeu; Timisoara, Romania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Can a tiny ultrasound probe stop bile duct stones from coming back?
Knowledge-focused CompletedThis study looked at whether using a special ultrasound probe (IDUS) during a procedure to remove bile duct stones can help predict if stones will come back. 248 adults at high risk for recurrence were randomly assigned to get IDUS or not. Researchers tracked stone return, need f…
Phase: NA • Sponsor: Shanghai Municipal Hospital of Traditional Chinese Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Pandemic Didn't stop this gallstone surgery from working
Knowledge-focused CompletedThis study looked at 237 patients who had a single surgery to remove both their gallbladder and any gallstones stuck in the bile duct. Researchers wanted to see if the COVID-19 pandemic changed how safe or effective this procedure was. They found that the surgery remained a good …
Sponsor: Imperial College London • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New stitching method may speed up gallstone surgery
Knowledge-focused CompletedThis study looked at 360 patients who had gallstone removal surgery with a T-tube drain. Doctors compared a new continuous stitching method to the traditional interrupted stitch for closing the bile duct. The goal was to see which method is faster and just as safe. Results could …
Sponsor: Yantai Affiliated Hospital of Binzhou Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Budget scope reuse tested for bile duct stone surgery
Knowledge-focused CompletedThis study looked at 75 patients in Nepal who had bile duct stones removed using a reused Ambu aScope, a cheap disposable scope normally used for breathing tubes. The goal was to see if reusing it is safe and effective in low-resource settings where expensive scopes aren't availa…
Sponsor: B.P. Koirala Institute of Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Deep sleep or light nod? study probes best sedation for gallstone procedure
Knowledge-focused CompletedThis study looked at over 121,000 procedures to remove gallstones from the bile duct using a scope (ERCP). Researchers wanted to see if the level of sedation given during the procedure affected whether stones were left behind. They found that deeper sedation might help the doctor…
Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC