Choledocholithiasis
MONDO:0006699Presence or formation of gallstones in the common bile duct.
44 clinical trials for this condition and its sub-types.
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New study tests single surgery to clear bile duct stones faster
Disease control OngoingThis study looks at 100 people with gallstones that have moved into the bile duct. One group gets the usual two-step treatment: first a scope to remove the bile duct stone, then surgery to remove the gallbladder. The other group gets a single surgery where the gallbladder is remo…
Phase: NA • Sponsor: Riga East Clinical University Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Robot takes the strain out of gallstone surgery
Disease control OngoingThis study compares a new robotic-assisted endoscope to the standard method for removing gallstones stuck in the common bile duct. The robot aims to protect doctors from radiation and repetitive strain injuries while keeping the procedure just as effective. About 200 adults with …
Phase: NA • Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Disease control
Last updated Jun 27, 2026 08:14 UTC
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New biomarkers may sharpen cancer diagnosis in bile duct blockages
Diagnosis OngoingThis study looks at whether measuring certain substances in bile and blood can more accurately diagnose cancer in people with bile duct blockages. Researchers will compare these new tests with standard methods in 500 adults undergoing a procedure called ERCP. The goal is to find …
Sponsor: AdventHealth • Aim: Diagnosis
Last updated Jun 27, 2026 09:02 UTC
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New wash may ease pain and nausea after gallbladder surgery
Symptom relief OngoingThis study tests whether adding the anti-nausea drug ondansetron to a standard saline wash during gallbladder surgery can better control pain and nausea afterward. Forty adults having their gallbladder removed will be randomly assigned to receive either a plain saline wash or one…
Phase: PHASE4 • Sponsor: Instituto Mexicano del Seguro Social • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Massive data dive aims to improve GI care
Knowledge-focused ENROLLING_BY_INVITATIONThis study is a registry that will review medical records of 1,000 patients treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will look at survival, symptoms like heartburn and swallowing trouble, and quality of life. The goal is to lear…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New registry aims to improve bile duct stone removal
Knowledge-focused OngoingThis study is a registry that collects information from patients who have a procedure called percutaneous cholangiopancreatoscopy (PCPS). During PCPS, doctors use a tiny camera to see inside the bile ducts and remove stones or take tissue samples. The goal is to learn how well th…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC