Central retinal vein occlusion

This phase 3 trial tests a single injection of SMO1, a dexamethasone implant placed inside the eye, for people with macular edema (swelling) caused by a blocked retinal vein. The study compares SMO1 to an existing dexamethasone implant to see which better improves vision and redu…

This study tests whether injecting a person's own bone marrow stem cells into or near the eye can help treat various retinal and optic nerve diseases, including age-related macular degeneration, retinitis pigmentosa, and glaucoma. Participants receive stem cell injections via dif…

This study tests a new eye injection called KIO-104 for people with macular edema, a condition where fluid builds up in the eye and blurs vision. About 28 adults will receive multiple doses to see if the drug is safe and helps reduce swelling. The goal is to find a steroid-free o…

This study tests a new eye imaging device (VG200D OCT) that takes detailed pictures of the retina. It compares these images to standard dye-based images (FA/ICGA) to see if the new device works just as well. About 30 adults with retina problems will take part. The goal is to see …

This study tests a special camera that takes detailed images of the retina using many wavelengths of light. Researchers hope it can find early signs of eye diseases like age-related macular degeneration, diabetic retinopathy, and glaucoma. About 1,000 adults in Melbourne, Austral…

This study tests a new MRI contrast agent called ferumoxytol, made from iron nanoparticles, to see if it can safely and effectively image veins in people with vein diseases. Current dyes can be risky for patients with kidney problems, but ferumoxytol may be safer and last longer …

This study tests a new dye called MB-102 for taking pictures of the back of the eye (retina) to diagnose conditions like diabetic retinopathy and macular degeneration. About 10 adults with healthy or diseased eyes will receive both the new dye and a standard dye to compare safety…

This study is creating a large collection of health information and biological samples (like blood, saliva, and eye tissue) from people with and without retinal diseases. Researchers aim to use this database to better understand conditions like age-related macular degeneration an…

This study uses a special eye scan (OCT angiography) to take detailed pictures of blood vessels in the back of the eye. Researchers will follow about 1,050 people with retinal diseases like diabetic retinopathy and healthy volunteers to see how these images can help detect early …

This study uses a special camera (adaptive optics) to take detailed pictures of the back of the eye in people with inherited retinal diseases. Researchers want to see how individual cells change over time and after treatments. About 200 participants aged 5 to 70 will be observed,…

This study gathers eye scan images from 180 people with healthy eyes or eye diseases like glaucoma and retinal disease. The goal is to collect data using a new optical coherence tomography (OCT) device called A10900. No treatment or medication is given. The information will help …

This study aims to create a database of eye images using a new holographic Doppler laser device. The goal is to better visualize and measure blood flow in the retina and choroid, which is important for diagnosing eye diseases. About 123 adults, both with and without eye condition…