New laser tech captures eye blood flow in unprecedented detail
NCT ID NCT06644196
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to create a database of eye images using a new holographic Doppler laser device. The goal is to better visualize and measure blood flow in the retina and choroid, which is important for diagnosing eye diseases. About 123 adults, both with and without eye conditions, will have their eyes imaged with this experimental laser. The images will be checked to see if they clearly show arteries and veins and can measure blood flow.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 123 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants will be recruited from ophthalmology consultations , or for participants with no ocular pathology, from staff, patients followed for a non-ophthalmological pathology or patient companions.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: For all participants: * Age ≥ 18 years * Having received informed information about the study and having signed a consent to participate in the study * Affiliated or beneficiary of social insurance For participants with no known ocular pathology: \- No known ocular pathology other than a refractive disorder For patients with optic nerve pathology: \- Patient undergoing ophthalmology consultation for optic nerve pathology in at least one eye (examples: glaucoma, optic neuritis, hereditary optic nerve diseases) For patients with retinal and/or choroidal pathology: \- Patients undergoing ophthalmology consultations for retinal and/or choroidal pathology in at least one eye (examples: diabetic retinopathy, age-related macular degeneration). For patients with retinal vascular pathology: \- Patient undergoing ophthalmology consultation for retinal vascular pathology in at least one eye (e.g. central retinal artery occlusion, central retinal vein occlusion, ocular ischemia syndrome). Exclusion Criteria: * Inability to maintain a stable sitting position * Contraindications to holographic doppler laser : * implanted medical electronic device (pacemaker or other) * history of photosensitivity. * received photo-dynamic therapy (PDT) within the last 3 months. * viral conjunctivitis or any other infectious disease. * skin lesions on the neck or forehead, not allowing contact with a chin strap * patients at high risk of damage from optical radiation (e.g. aphakic patients, or patients with reduced sensitivity to light due to disease of the back of the eye).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hôpital Fondation A. de Rothschild
RECRUITINGParis, 75019, France