Eye implant could restore sight after retinal vein blockage
NCT ID NCT07708142
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This phase 3 trial tests a single injection of SMO1, a dexamethasone implant placed inside the eye, for people with macular edema (swelling) caused by a blocked retinal vein. The study compares SMO1 to an existing dexamethasone implant to see which better improves vision and reduces swelling over six months. Participants are adults with branch or central retinal vein occlusion and significant vision loss. The goal is to find a safe, effective treatment to help restore sight.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a dexamethasone intravitreal implant (SMO1)
- What this could lead to
- If successful, SMO1 could offer a new treatment option for people with vision loss due to retinal vein occlusion, potentially improving sight with a single injection.
- What could go wrong
- This is a phase 3 trial comparing SMO1 to an existing drug, so it may not prove superior. Eye injections carry risks like infection, increased eye pressure, or cataract formation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for RETINAL VEIN OCCLUSION WITH MACULAR EDEMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Kyung Hee University Hospital at Gangdong
RECRUITINGSeoul, Gangdong-gu, 05278, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••