Barrett esophagus

This study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …

This study compared two endoscopic treatments for Barrett's esophagus, a condition that can lead to esophageal cancer. The goal was to see which procedure—radiofrequency ablation or hybrid argon plasma coagulation—causes less pain and is safer from the patient's viewpoint. Sixty-…

This study tested a procedure called radiofrequency ablation (using heat to remove abnormal cells) in 125 people with Barrett's esophagus and low-grade dysplasia. Participants were randomly assigned to receive the ablation or regular endoscopic monitoring. The goal was to see if …

This study tested a new, office-based test called EsoCheck/EsoGuard to detect Barrett's esophagus in 132 people who do not have chronic heartburn but have other risk factors like being over 50, white, male, or having central obesity. Participants swallowed a capsule on a string t…

This study tested a new way to spot cancer in people with Barrett's esophagus, a condition that can lead to esophageal cancer. Doctors sprayed a weak vinegar solution on the esophagus and timed how long the tissue stayed white. They found that cancerous or pre-cancerous areas los…

This study tested whether a special camera technique (virtual chromoendoscopy) can find pre-cancerous or cancerous spots in Barrett's esophagus better than the standard method of taking random biopsies. 110 adults with Barrett's esophagus took part. The goal was to see if the new…

This study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…

This study tested whether giving a small amount of s-ketamine during chest surgery could reduce the risk of postoperative delirium (sudden confusion) in patients aged 60 and older. Over 500 participants were randomly assigned to receive either s-ketamine or another drug (dexmedet…

This early study looked at how two approved constipation drugs, plecanatide and linaclotide, affect a chemical called cGMP in the small intestine. Researchers compared tissue samples from 43 adults with Barrett esophagus or GERD who took either drug or no drug. The goal was to me…

This completed study looked at 100,000 patient records to find out if people with eosinophilic esophagitis (EoE) are more likely to develop esophageal cancer. The researchers wanted to see if any increased risk is due to EoE itself or to other conditions like acid reflux or Barre…

This study looked at whether a non-endoscopic device (EsoCheck) and a biomarker test (EsoGuard) can help doctors decide when to refer patients for a standard upper endoscopy to screen for Barrett's esophagus. 97 doctors reviewed patient cases and made referral decisions, first wi…

This completed study surveyed over 700 primary care doctors, gastroenterologists, and patients across seven U.S. health systems. The goal was to find out what knowledge gaps, attitudes, and practical barriers prevent people from getting screened for Barrett's esophagus, a conditi…