Bacterial vaginosis
MONDO:0005316Infection caused by bacterial overgrowth in the vagina. Most affected women are asymptomatic. When symptoms occur, they include foul-smelling vaginal discharge, vaginal itching, and burning. Risk factors include sexual activity with multiple partners and the use of vaginal douches and intrauterine devices. Up to a third of cases resolve without treatment. Antibiotic treatment is recommended when symptoms are present and for women that are pregnant at the time of infection.
Also known as: BV
90 clinical trials for this condition and its sub-types.
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Can a vaginal probiotic stick around? new study follows women who got the treatment
Disease control ENROLLING_BY_INVITATIONThis study is for women who previously received a vaginal probiotic (LC106) for bacterial vaginosis in an earlier trial. Researchers want to see if the good bacteria from the probiotic can stay in the vagina over time. About 71 women will be followed, and the main goal is to chec…
Phase: EARLY_PHASE1 • Sponsor: Caroline Mitchell • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Hospital at home: new study tests home care for infections
Disease control OngoingThis study looks at whether a special team of doctors and nurses can treat adults with suspected infections at home, instead of sending them to the hospital. About 500 people will be randomly assigned to either standard hospital care or home-based care from a mobile response team…
Phase: NA • Sponsor: Copenhagen University Hospital at Herlev • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Personalized antibiotic dosing may boost infection treatment
Disease control OngoingThis study tests whether using personalized dosing (based on drug levels in the blood) for the antibiotic teicoplanin works better than standard dosing for treating bacterial infections. About 74 adults in hospital intensive care or other units will take part. The goal is to see …
Phase: PHASE4 • Sponsor: Radboud University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Pharmacists take on heart disease: new study tests community-based risk reduction
Disease control OngoingThis study tests whether a pharmacist-led program can help people reduce their risk of heart disease. Over 1,000 adults with conditions like diabetes, high blood pressure, or obesity are taking part. Pharmacists use a step-by-step guide to assess risk and support lifestyle change…
Phase: NA • Sponsor: University of Alberta • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Could a simple cup cut STIs and BV? new trial hopes so
Disease control OngoingThis study tests whether giving menstrual cups to economically vulnerable women in Kenya can lower rates of bacterial vaginosis (BV) and sexually transmitted infections (STIs). The cup is a reusable silicone device that collects menstrual blood and can be worn during sex. Researc…
Phase: PHASE2 • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Could a 'Flora Transplant' stop recurring vaginal infections?
Disease control OngoingThis study tests whether transferring healthy vaginal bacteria from donors can cure recurrent bacterial vaginosis (BV). Ten women with frequent BV will receive the transplant. The goal is to restore natural balance and prevent repeat infections without antibiotics.
Phase: NA • Sponsor: Hadassah Medical Organization • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Study to prevent preterm birth by frequent vaginal infection screening abandoned
Prevention TerminatedThis study aimed to find out if checking pregnant women for bacterial vaginosis every two weeks could reduce the chance of early delivery. It planned to include women with a history of preterm birth. However, the trial was withdrawn before any participants were enrolled, so no re…
Phase: NA • Sponsor: Loma Linda University • Aim: Prevention
Last updated Jun 26, 2026 16:46 UTC
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NIH launches Long-Term observation of inflammatory diseases
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows up to 500 people with acute or chronic inflammatory disorders, such as infections or immune problems, over time. Researchers will monitor participants with standard tests and may screen them for other studies. The goal is to better understand these conditions a…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Scientists hunt for genetic clues in blood and urine to personalize lung cancer care
Knowledge-focused OngoingThis study collects blood, urine, and tissue samples from 330 adults with advanced lung or head and neck cancer to improve precision medicine. Researchers will analyze genetic changes in these samples and grow some tumors in mice to compare DNA. The goal is to refine liquid biops…
Phase: NA • Sponsor: University of Arkansas • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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AI predicts hospital stays, but study never started
Knowledge-focused TerminatedThis study aimed to see if a computer could learn to predict how long a patient would stay in a home hospital program. Researchers planned to use data from past patients to train the computer. However, the study was withdrawn before any patients were enrolled, so no results are a…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Resident's journey to master scarless hysterectomy under the microscope
Knowledge-focused OngoingThis study watches a single gynecology resident as they learn to perform a hysterectomy through the vagina using a special camera, leaving no belly scars. The goal is to see how quickly the resident improves, measuring surgery time and any complications. Nineteen women with benig…
Sponsor: Cukurova University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Quick STI tests may slash unneeded antibiotics for vaginal discharge
Knowledge-focused OngoingThis study in Nepal tests whether using rapid point-of-care tests for sexually transmitted infections can reduce the overuse of antibiotics for vaginal discharge. About 1,500 women will be split into three groups: standard care, test-guided treatment, or test-guided treatment plu…
Phase: NA • Sponsor: Norwegian University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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New biobank aims to unlock secrets of infertility and pregnancy
Knowledge-focused ENROLLING_BY_INVITATIONThis study is creating a biobank—a collection of blood samples and health data—to help researchers better understand gynecological disorders, infertility in men and women, and pregnancy-related conditions. Up to 3,000 participants will provide samples at San Raffaele Hospital in …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Immune cell showdown: autoimmune vs. infection vs. healthy
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at immune cells from people with autoimmune diseases (like lupus), people with infections, and healthy volunteers. Researchers want to understand how these cells differ and what makes them attack the body in autoimmune conditions. The study involves blood and bon…
Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC