Can a vaginal probiotic stick around? new study follows women who got the treatment
NCT ID NCT07305844
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is for women who previously received a vaginal probiotic (LC106) for bacterial vaginosis in an earlier trial. Researchers want to see if the good bacteria from the probiotic can stay in the vagina over time. About 71 women will be followed, and the main goal is to check if the probiotic bacteria are still present at meaningful levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LC106 (a vaginal tablet containing 6 strains of Lactobacillus crispatus)
What this could lead to
If successful, this could show that the probiotic consistently colonizes the vagina, pointing toward a way to restore healthy bacteria and reduce recurrent bacterial vaginosis.
What could go wrong
This is a very early (Phase 1), small, open-label study with no placebo group, so results may not prove effectiveness. The probiotic may not colonize as expected or could cause irritation.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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CAPRISA
Vulindlela, South Africa
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States