Autosomal recessive juvenile Parkinson disease 2
MONDO:0010820A group of disorders which feature impaired motor control characterized by bradykinesia, muscle rigidity; tremor; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see Parkinson disease), secondary parkinsonism (see Parkinson disease, secondary) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the basal ganglia.
Also known as: PRKN young-onset Parkinson disease, Parkinson disease, juvenile, type 2, autosomal recessive juvenile Parkinson disease 2, autosomal recessive juvenile Parkinson disease type 2, young-onset Parkinson disease caused by mutation in PRKN, JP, PARK2, PDJ
13 clinical trials for this condition and its sub-types.
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New PET scan could slash radiation by 100x
Diagnosis ENROLLING_BY_INVITATIONThis study tests a new PET imaging technique that uses 10 to 100 times less radiation than standard scans. Researchers will inject 200 healthy volunteers and patients with a radioactive tracer and use a high-sensitivity scanner to see if image quality remains good enough for dete…
Phase: PHASE2 • Sponsor: Akiva Mintz • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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AI boosts brain scan accuracy in massive new trial
Diagnosis ENROLLING_BY_INVITATIONThis study tests whether an AI tool can help radiologists read brain CT and MRI scans more accurately and quickly. Researchers will compare how well doctors, AI alone, and doctors using AI together can spot abnormalities, urgent findings, and classify diseases. The goal is to red…
Sponsor: Yaou Liu • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC
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Scientists hunt for clues to diagnose Parkinson's earlier
Knowledge-focused OngoingThis study aims to identify biomarkers—biological clues in the body—that can help distinguish between Parkinson's disease and similar conditions like progressive supranuclear palsy and multiple system atrophy. Researchers will follow people with early-stage parkinsonism and healt…
Sponsor: Non-profit organization for scientific research in Parkinson's disease and related disorders • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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300 volunteers help create medical image bank for science
Knowledge-focused OngoingThis study gathers MRI, CT, and ultrasound images from 300 adults—some healthy, some with kidney or brain disease—to build a collection for future not-for-profit research. No new treatments are being tested; the goal is to make medical images available to scientists for advancing…
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:28 UTC