Autosomal recessive juvenile Parkinson disease 2
MONDO:0010820A group of disorders which feature impaired motor control characterized by bradykinesia, muscle rigidity; tremor; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see Parkinson disease), secondary parkinsonism (see Parkinson disease, secondary) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the basal ganglia.
Also known as: PRKN young-onset Parkinson disease, Parkinson disease, juvenile, type 2, autosomal recessive juvenile Parkinson disease 2, autosomal recessive juvenile Parkinson disease type 2, young-onset Parkinson disease caused by mutation in PRKN, JP, PARK2, PDJ
13 clinical trials for this condition and its sub-types.
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Can a One-Time bone drug shield Parkinson's patients from fractures?
Prevention CompletedThis study tested whether a single infusion of zoledronic acid (Reclast) can prevent fractures in men and women aged 60 and older with Parkinson's disease or related conditions. Over 2,700 participants were randomly assigned to receive either the drug or a placebo, and were follo…
Phase: PHASE4 • Sponsor: California Pacific Medical Center Research Institute • Aim: Prevention
Last updated Jun 27, 2026 14:01 UTC
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Bubble therapy shows promise for Parkinson's symptoms
Symptom relief CompletedThis study tested whether infusing tiny bubbles of oxyhydrogen gas could help people with Parkinsonism. 35 adults received the infusion alongside their usual care. Researchers measured changes in disease severity, thinking ability, and quality of life. The goal was to see if this…
Phase: PHASE2, PHASE3 • Sponsor: dr. Siti Nurlaela, SpN • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Scientists dig into DNA to unlock secrets of early Parkinson's
Knowledge-focused CompletedThis completed study looked at 31 people with early-onset Parkinson's disease (starting before age 50) and their family members to find genetic causes. Researchers collected blood and skin samples to study DNA and create cell lines. The goal was to better understand which gene mu…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Parkinson's Patients' hospital stays under the microscope
Knowledge-focused CompletedThis completed study looked at over 2,500 people with Parkinson's disease who were admitted to the hospital through the emergency room. Researchers wanted to find the main reasons for these hospital stays and compare them to people of the same age without Parkinson's. The goal wa…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC