Autosomal recessive juvenile Parkinson disease 2
MONDO:0010820A group of disorders which feature impaired motor control characterized by bradykinesia, muscle rigidity; tremor; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see Parkinson disease), secondary parkinsonism (see Parkinson disease, secondary) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the basal ganglia.
Also known as: PRKN young-onset Parkinson disease, Parkinson disease, juvenile, type 2, autosomal recessive juvenile Parkinson disease 2, autosomal recessive juvenile Parkinson disease type 2, young-onset Parkinson disease caused by mutation in PRKN, JP, PARK2, PDJ
13 clinical trials for this condition and its sub-types.
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Could stem cells ease Parkinson's symptoms? new trial launches
Disease control Not yet recruitingThis study tests two types of stem cell treatments for people with Parkinsonism, a condition that causes movement and non-movement problems. The goal is to see if these treatments are safe and can improve symptoms like tremors, stiffness, and mood changes. About 120 adults aged 4…
Phase: PHASE2 • Sponsor: Biocells Medical • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Could zapping the spine steady blood pressure in Parkinson's?
Disease control Not yet recruitingThis study tests whether spinal cord stimulation can help people with Parkinson's disease who experience sudden drops in blood pressure when standing up. Forty participants will receive either an implanted stimulator or a non-invasive version. The goal is to see if the treatment …
Phase: NA • Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Scientists launch 5-year watch on rare genetic Parkinson's to unlock disease secrets
Knowledge-focused Not yet recruitingThis study follows 70 people with PRKN- or PINK1-linked Parkinson's disease, as well as those with typical Parkinson's and healthy volunteers, over 5 years. Researchers will track movement, thinking, and mood symptoms, and collect blood, urine, and optional spinal fluid or muscle…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC