Scientists launch 5-year watch on rare genetic Parkinson's to unlock disease secrets

NCT ID NCT07613112

First seen Jun 26, 2026 · Last updated Aug 14, 2026 · Updated 3 times

Summary

This study follows 70 people with PRKN- or PINK1-linked Parkinson's disease, as well as those with typical Parkinson's and healthy volunteers, over 5 years. Researchers will track movement, thinking, and mood symptoms, and collect blood, urine, and optional spinal fluid or muscle samples. The goal is to better understand how these genetic forms of Parkinson's progress, which could help design future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could reveal how genetic forms of Parkinson's progress, pointing toward better monitoring or future treatments.
What could go wrong
This is an observational study, not a treatment trial. It may not lead directly to new therapies, and results may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

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Other studies related to the condition(s) this trial covers.