Autosomal dominant prognathism

This study tested a special dental appliance to correct underbite (Class III malocclusion) in 36 children aged 7 to 12. The device combines a fixed inclined plane on the lower front teeth with rotated brackets on the upper front teeth to encourage proper jaw growth. After 6 month…

This study tested a modified jaw surgery (Le Fort I osteotomy) in 9 adults with cleft lip and palate who also had a misaligned bite and a bone gap in the upper jaw. The surgery aimed to improve facial structure and reduce the size of the bone defect. Researchers measured changes …

This study tested two methods to correct underbite (skeletal Class III malocclusion) in 14 growing children. One group used a traditional tooth-borne anchor with a face mask, while the other used a palatal plate with a face mask. The goal was to see which approach better moves th…

This study tested two ways to pull the upper jaw forward in 40 children aged 7-13 with underbite. One method used a traditional face mask attached to teeth, the other used tiny screws placed in the cheekbone. Both followed a special expansion protocol. The goal was to see which a…

This study compared three treatments for children aged 9-12 with a forward lower jaw (Class III malocclusion): a face mask with expander, a mini maxillary protractor, and a chin cup with elastics. Fifty-five children were treated, and researchers measured changes in facial bones …

This study looked at 31 people with a type of jaw misalignment called skeletal Class III deformity. Researchers compared how the face's soft tissues changed after two types of jaw surgery: a minimally invasive approach and a conventional one. Using 3D imaging, they measured diffe…

This study looked at a treatment called "Surgery-First" for people with a severe underbite (skeletal Class III malocclusion). Instead of wearing braces before surgery, patients had jaw surgery first to fix the bone problem, then braces afterward. Researchers studied 60 patients u…

This study looked at 24 adults with a specific jaw misalignment (Class III) who needed double-jaw surgery. Researchers compared two different surgical timings—surgery first versus surgery early—to see how they affected tooth root length and volume, as well as facial soft tissues.…

This study tested whether a powerful DNA test called high-throughput exome sequencing can find genetic causes of multiple birth defects in fetuses when standard exams fail. Researchers studied 100 fetuses with at least two malformations and no prior diagnosis. They compared the n…

This study tested whether a fast type of genetic test called rapid genome sequencing can find the cause of birth defects seen on ultrasound more quickly than current methods. Researchers included 184 pregnancies with certain ultrasound findings. The goal was to see if results cou…

This completed study looked at how accurately a custom-made implant (called a PSI) could reposition the lower jaw during surgery for overbite or underbite. Eight patients aged 18-40 who needed jaw surgery received the custom implant. The researchers compared the planned jaw posit…