Autosomal dominant prognathism
MONDO:0008312Malocclusion in which the mandible is anterior to the maxilla as reflected by the first relationship of the first permanent molar (mesioclusion).
Also known as: 'Habsburg jaw', 'Hapsburg jaw', Habsburg jaw, Hapsburg jaw, prognathism mandibular, prognathism, mandibular
24 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New dental device aims to fix underbite without surgery
Disease control CompletedThis study tested a special dental appliance to correct underbite (Class III malocclusion) in 36 children aged 7 to 12. The device combines a fixed inclined plane on the lower front teeth with rotated brackets on the upper front teeth to encourage proper jaw growth. After 6 month…
Phase: NA • Sponsor: Can Tho University of Medicine and Pharmacy • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New jaw surgery shows promise for cleft lip and palate patients
Disease control CompletedThis study tested a modified jaw surgery (Le Fort I osteotomy) in 9 adults with cleft lip and palate who also had a misaligned bite and a bone gap in the upper jaw. The surgery aimed to improve facial structure and reduce the size of the bone defect. Researchers measured changes …
Phase: PHASE4 • Sponsor: Alexandria University • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New palatal plate may improve underbite correction in kids
Disease control CompletedThis study tested two methods to correct underbite (skeletal Class III malocclusion) in 14 growing children. One group used a traditional tooth-borne anchor with a face mask, while the other used a palatal plate with a face mask. The goal was to see which approach better moves th…
Phase: NA • Sponsor: Faculty of Dental Medicine for Girls • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New face mask technique may fix underbite without surgery
Disease control CompletedThis study tested two ways to pull the upper jaw forward in 40 children aged 7-13 with underbite. One method used a traditional face mask attached to teeth, the other used tiny screws placed in the cheekbone. Both followed a special expansion protocol. The goal was to see which a…
Phase: NA • Sponsor: Murat Kaan Erdem • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Which jaw correction works best? study tests three methods in kids
Disease control CompletedThis study compared three treatments for children aged 9-12 with a forward lower jaw (Class III malocclusion): a face mask with expander, a mini maxillary protractor, and a chin cup with elastics. Fifty-five children were treated, and researchers measured changes in facial bones …
Phase: NA • Sponsor: TC Erciyes University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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AI takes on orthodontic diagnosis: can it match expert dentists?
Diagnosis CompletedThis study compares an artificial intelligence (AI) system called WebCeph with the traditional way orthodontists diagnose and plan treatment for misaligned teeth (malocclusion). Researchers will use routine dental records from 120 new patients aged 12 and older. Each case will be…
Sponsor: Ben Hafeed Dental Center • Aim: Diagnosis
Last updated Jul 10, 2026 00:00 UTC
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The genetic clues behind underbites: a new study digs deep
Knowledge-focused CompletedThis study looks at whether certain genetic variations are linked to a type of underbite called skeletal Class III malocclusion. Researchers will collect saliva samples, facial photos, and X-rays from people with and without the condition to compare their DNA. The goal is to iden…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Aug 08, 2026 00:03 UTC
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Bite by bite: jaw differences in vietnamese teens could sharpen orthodontic care
Knowledge-focused CompletedThis study looks at how the shape of the jaw and dental arches differs among teenagers aged 15 to 18 with three common types of misaligned bites (Class I, II, and III). Researchers in Vietnam used X-rays and 3D scans to measure facial bones, teeth, and soft tissues. The goal is t…
Sponsor: Can Tho University of Medicine and Pharmacy • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Less invasive jaw surgery may change face shape differently, study finds
Knowledge-focused CompletedThis study looked at 31 people with a type of jaw misalignment called skeletal Class III deformity. Researchers compared how the face's soft tissues changed after two types of jaw surgery: a minimally invasive approach and a conventional one. Using 3D imaging, they measured diffe…
Phase: NA • Sponsor: TC Erciyes University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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New study measures how well Surgery-First fixes jaw problems
Knowledge-focused CompletedThis study looked at a treatment called "Surgery-First" for people with a severe underbite (skeletal Class III malocclusion). Instead of wearing braces before surgery, patients had jaw surgery first to fix the bone problem, then braces afterward. Researchers studied 60 patients u…
Phase: NA • Sponsor: Hanoi Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Timing of jaw surgery may affect tooth roots and facial changes
Knowledge-focused CompletedThis study looked at 24 adults with a specific jaw misalignment (Class III) who needed double-jaw surgery. Researchers compared two different surgical timings—surgery first versus surgery early—to see how they affected tooth root length and volume, as well as facial soft tissues.…
Phase: NA • Sponsor: Gokhan Coban • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Custom jaw implants put to the test: will they improve surgery precision?
Knowledge-focused CompletedThis completed study looked at how accurately a custom-made implant (called a PSI) could reposition the lower jaw during surgery for overbite or underbite. Eight patients aged 18-40 who needed jaw surgery received the custom implant. The researchers compared the planned jaw posit…
Phase: NA • Sponsor: Faculty of Dental Medicine for Girls • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC