Autism spectrum disorder
MONDO:0005258A spectrum of developmental disorders that includes autism, and Asperger syndrome. Signs and symptoms include poor communication skills, defective social interactions, and repetitive behaviors.
Also known as: autism spectrum disorder, autistic spectrum disorder, pervasive developmental disorder - not otherwise specified, pervasive developmental disorders, atypical autism
684 clinical trials for this condition and its sub-types.
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Broader categories
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Virtual coaching for toddlers with autism shows promise but trial cut short
Disease control TerminatedThis study tested a completely virtual early intervention program for toddlers with autism, using telehealth coaching to help parents embed learning into daily activities. Researchers planned to enroll 240 children from eight US regions, but the trial was terminated early with on…
Phase: NA • Sponsor: Florida State University • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Mental health sessions may boost vaccine uptake in latinx communities
Prevention TerminatedThis study tested whether adding vaccine discussions to routine behavioral health visits could reduce hesitancy and increase COVID-19 and flu shots among Latinx adults with mental illness. Clinicians used motivational interviewing and could offer a warm handoff to a nurse for vac…
Phase: NA • Sponsor: Boston College • Aim: Prevention
Last updated Jun 26, 2026 17:00 UTC
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Autism social trial halted: memantine shows no promise
Symptom relief TerminatedThis study tested whether memantine, a medication for Alzheimer's, could improve social skills in youth aged 8-18 with autism or nonverbal learning disability. The trial was stopped early after enrolling only 25 participants. The main goal was to measure changes in social functio…
Phase: PHASE3 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Autism irritability drug trial ends early: what happened?
Symptom relief TerminatedThis study looked at the long-term safety of pimavanserin for treating irritability in children and teens (ages 5-17) with autism. It was an extension of an earlier 6-week study, lasting 52 weeks. The trial was terminated early, and results are not yet fully available.
Phase: PHASE2, PHASE3 • Sponsor: ACADIA Pharmaceuticals Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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5-Minute wellness program for caregivers shows promise, study cut short
Symptom relief TerminatedThis study tested a program called 5Minutes4Myself, designed to help caregivers of autistic children (ages 8-21) manage stress and improve their well-being. Participants worked with a coach to create a personalized wellness plan and used a phone app with reminders and mindfulness…
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Glutathione study for autism fizzles out early
Symptom relief TerminatedThis study aimed to see if taking glutathione by mouth is safe and practical for children and teens with autism. Researchers planned to enroll 24 participants but stopped early with only 6. The goal was to measure changes in behavior and social skills over 12 weeks.
Phase: PHASE4 • Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 26, 2026 18:02 UTC
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Sibling power: could brothers and sisters be the key to autism therapy?
Symptom relief TerminatedThis study explored whether training typically developing siblings to teach reading and social skills can help children with autism. The approach used a simple teaching method called model-lead-test, where the sibling shows, practices, and gives feedback. Only 8 families took par…
Phase: NA • Sponsor: Arizona State University • Aim: Symptom relief
Last updated Jun 26, 2026 16:44 UTC
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Brain and eye clues to emotion recognition in autism and psychosis
Knowledge-focused TerminatedThis study aimed to understand why people with autism or schizophrenia sometimes struggle to recognize emotions on faces. Researchers used brain wave recordings (EEG) and eye-tracking to see how participants processed facial expressions. The study included people with autism, sch…
Phase: NA • Sponsor: Hôpital le Vinatier • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Brain scans reveal how autistic people process sensory overload
Knowledge-focused TerminatedThis study aimed to understand why people with autism often feel overwhelmed by sensory input like bright lights or loud noises. Researchers planned to use virtual reality and brain scans to see how the brain reacts to unpleasant visual stimuli. The study was terminated early and…
Phase: NA • Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Mental health study aims to uncover Long-Term heart risks
Knowledge-focused TerminatedThis study followed 167 adults with mental health issues like anxiety, depression, or sleep problems who visited their primary care doctor. Researchers used health conversations and a blood test to track lifestyle changes and heart disease risks over up to 20 years. The goal was …
Phase: NA • Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Can an eHealth program help teachers support kids with ADHD, autism, and learning disabilities?
Knowledge-focused TerminatedThis study tested an online program called Teacher Help, designed to train teachers in evidence-based strategies for students with ADHD, autism spectrum disorder, or learning disabilities. Teachers worked through six online sessions with support from school psychologists. The goa…
Phase: NA • Sponsor: IWK Health Centre • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC