Brain training: behavioral therapy may rewire social circuits in autistic toddlers

NCT ID NCT03427138

Terminated Disease control Sponsor: Boston University Charles River Campus Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study investigates whether a 10-week behavioral intervention called JASPER can improve early communication skills and alter brain activity in toddlers and preschoolers with autism. Participants aged 18 to 59 months receive twice-weekly sessions focused on joint attention and play. Researchers measure changes using EEG brain scans, eye-tracking, and behavioral assessments to see if therapy affects the mirror neuron system.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a behavioral intervention called JASPER (Joint Attention Symbolic Play Engagement Regulation)
What this could lead to: If successful, this could show that early behavioral therapy changes both social communication skills and brain function in young children with autism.
What could go wrong: This is a small, early-stage study with no control group, so results may not be generalizable. The intervention requires significant parent and child commitment.

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Conditions

The condition(s) this trial relates to.

autism spectrum disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTISM SPECTRUM DISORDER

Contacts and locations

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Locations

Boston University

Boston, Massachusetts, 02215, United States

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