Anterior uveitis

This study tests whether certolizumab pegol (Cimzia), a drug already used for arthritis, can reduce flares of anterior uveitis—a painful eye inflammation—in people with axial spondyloarthritis who have had uveitis before. About 89 adults with active axial spondyloarthritis and a …

This phase 3 trial tested TRS01 eye drops in 142 people with active non-infectious anterior uveitis, an inflammatory eye condition that can cause pain and vision loss. Participants used the drops four times a day, and researchers measured how well the drug reduced inflammation co…

This study tested two different steroid eye drops—loteprednol and prednisolone—in 66 children with inflammatory nodules in the front part of the eye. The goal was to see if loteprednol could control inflammation as well as prednisolone while causing fewer increases in eye pressur…

This study tested a new method called metagenomic deep sequencing (MDS) to find the cause of eye infections. 100 adults with suspected infectious uveitis or endophthalmitis were randomly assigned to have their doctors receive MDS results or not, in addition to standard tests. The…

This study tested whether a smartphone meditation app (Calm Health) could help reduce anxiety and depression in 100 adults with non-infectious uveitis, an inflammatory eye disease. Participants used the app and reported their symptoms. The goal was to see if digital mindfulness c…

This study tested whether a tiny eye insert called DEXTENZA, placed after cataract surgery, works better than standard eye drops alone for reducing pain and swelling. Fifty adults having cataract surgery took part. The insert slowly releases medicine over time, aiming to improve …

This study compared gum health and levels of inflammatory substances in the mouth and blood of 25 people with non-infectious uveitis (an eye inflammation) and 27 healthy individuals. Researchers measured gum pocket depth, bleeding, and cytokines like TNF-α and IL-10. The goal was…