Anogenital human papillomavirus infection

This phase 3 study tested the 9-valent HPV vaccine (Gardasil 9) in over 1,000 Japanese males aged 16 to 26. The goal was to see if the vaccine could prevent persistent HPV infections that can lead to genital warts and anal cancers. Participants received either the vaccine or a pl…

This trial compares two surgical methods—carbon dioxide laser ablation and electrocoagulation—for removing genital warts in women. The main goal is to see which technique gives a better cosmetic result six weeks after treatment. Researchers also track operation time, complication…

This study tested whether giving the HPV vaccine (Gardasil) to women with large or extensive genital warts before surgery could prevent the warts from coming back. The trial included 52 women, some with HIV and some without. Researchers measured changes in wart size and antibody …

This small pilot study tested whether injecting the Gardasil 9 HPV vaccine directly into genital warts could reduce their size and number. Only 2 adults with at least 3 warts each took part. The goal was to see if this approach is safe and worth studying further.

This completed study examined 217 Hispanic people living with HIV in California, Mexico, and Puerto Rico to see if the types of bacteria in the anus are linked to high-risk HPV infection and pre-cancerous lesions. Researchers collected anal swabs and questionnaires to compare mic…