Can a vaccine prevent genital warts from returning after surgery?
NCT ID NCT02750202
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving the HPV vaccine (Gardasil) to women with large or extensive genital warts before surgery could prevent the warts from coming back. The trial included 52 women, some with HIV and some without. Researchers measured changes in wart size and antibody levels over 60 weeks to see if the vaccine boosted the immune response and improved outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Quadrivalent HPV vaccine (Gardasil)
- What this could lead to
- If it works, this could offer a way to reduce the high recurrence rate of genital warts after surgery, especially in women with HIV.
- What could go wrong
- This is a small, completed Phase 3 trial with only 52 participants, so results may not apply to everyone. The vaccine may not prevent recurrence in all cases.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GENITAL WARTS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Steve Biko Academic Hospital
Pretoria, Gauteng, South Africa
-
Tygerberg Hospital
Cape Town, Western Cape, South Africa
More trials for these conditions
Other studies related to the condition(s) this trial covers.