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127005 trials found · Page 6081 of 6351
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Healthcare workers speak out: new survey exposes hidden violence on the job
Knowledge-focused CompletedWorkplace violence includes physical and verbal aggression as well as threatening behavior. All types of workplace violence incidents in health care are often under-reported, especially if there is no lasting physical injury.
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Scientists probe gut to see how drugs really dissolve
Knowledge-focused CompletedIn vivo drug dissolution in the gastrointestinal (GI) tract is largely unmeasured. The purpose of this clinical study is to evaluate the in vivo drug dissolution and systemic absorption of modified release formulations of the BCS Class II drug Glipizide by direct sampling of stom…
Phase 1 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Why did women skip a breast cancer trial? COVID money woes may be key
Knowledge-focused Stopped earlyThe purpose of this study is to find out whether factors that lead Women of Color to decline participation in the breast cancer screening trial EA1151 (TMIST) differ from non-women of color.
Sponsor: Eastern Cooperative Oncology Group • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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Smart braces chip tracks wear time in kids
Knowledge-focused CompletedThis randomized controlled trial aims to evaluate whether thermosensory wear-time documentation improves patient compliance of removable orthodontic appliances treated in a public health care clinic. The patients are children and adolescents.
Sponsor: University of Helsinki • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Study checks safety of combining two pain drugs in abdominal surgery
Knowledge-focused CompletedThoracic epidural analgesia (TEA) is the gold standard analgesia of the laparotomy in major abdominal surgery and can be associated with intravenous lidocaine or subtituted by intravenous lidocaine when TEA is contraindicated and in order to reduce the use of the morphinics in th…
Phase 4 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Diabetes may change how fast the stomach empties before surgery
Knowledge-focused CompletedComparison of residual gastric volume measure by ultrasounds between diabetic and non-diabetic patients scheduled for elective surgery
Sponsor: Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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New Frown-Line treatment shows promise in large trial
Symptom relief CompletedFacial lines that develop from repeated facial expression, such as glabellar lines (GL), are typically treated by selectively weakening specific muscles with small quantities of botulinum toxin. AGN-151586 is an investigational product being developed for the treatment of GL. The…
Phase 3 • Sponsor: AbbVie • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Heart device data drive: 1,000 patients help shape Tomorrow's implants
Knowledge-focused OngoingThe study is designed to collect data on Cardiovascular Implantable Electronic Device (CIED) information, implant procedure details, and/or patient characteristics to support development of future CIED products and procedures.
Sponsor: Medtronic Cardiac Rhythm and Heart Failure • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Electric toothbrush battle: which brush wins for whiter teeth?
Symptom relief CompletedThe objective of the present study was to compare the effects of reduction of extrinsic stains between 2 commercially available Oclean sonic toothbrushes in comparison with an Oral-B manual toothbrush.
Sponsor: Sun Yat-sen University • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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PTSD drug safety study halted early: what we know
Knowledge-focused Stopped earlyAbout 6.4% of the U.S. population suffers from posttraumatic stress disorder (PTSD). Trauma-focused psychotherapies are generally effective in PTSD, but responses vary greatly across individuals and PTSD subpopulations. Neurobiological factors impacted by life experiences, stress…
Phase 2 • Sponsor: Boston University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Inside the brain: how a common sedative eases pain
Knowledge-focused CompletedNeuroimaging data will be collected for patients that are given low doses of dexmedetomidine in order to understand its analgesic effects.
Phase 2/3 • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Can a monitor read pain in sleeping kids?
Knowledge-focused CompletedThe Nociception Level (NoL) is an index obtained via a non-invasive monitor, that is currently used to assess nociception in anesthetized adults. The NoL index varies from 0 to 100. It increases in response to nociceptive stimuli. The objective of this study was to investigate if…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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New registry aims to track brain infection outcomes
Knowledge-focused Recruiting nowCentral Nervous System (CNS) infections are considered rare conditions but at the same time, they are emergencies whose diagnosis and treatment are time-dependent. They include several clinical syndromes, including meningitis, encephalitis, brain abscesses, and post-surgical meni…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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GripAble gadget tested for spasticity rehab after botox shots
Knowledge-focused CompletedThe purpose of this study is to explore how a rehabilitation tool (GripAble) could be used to monitor the effect of BoNT-A during an injection cycle and understand its potential value as a home rehabilitation tool in routine practice.
Sponsor: Ipsen • Aim: Knowledge-focused
Last updated Jun 26, 2026 19:02 UTC
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Nicotine myths: study reveals how messaging shapes smoker beliefs
Knowledge-focused CompletedThe purpose of this study is to examine the effect of nicotine messaging and nicotine content of study cigarettes on nicotine beliefs and subsequent use of tobacco and nicotine products.
Sponsor: Andrew Strasser • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Hidden weakness after ACL surgery revealed by jump test
Knowledge-focused CompletedPurpose: This study aims to better understand how force is produced during a vertical jump in individuals approximately six months after anterior cruciate ligament reconstruction compared with healthy individuals. After this type of knee surgery, many patients recover well clinic…
Sponsor: Haute Ecole ARC Sante • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Heart attack inflammation: small study maps CRP changes after emergency procedure
Knowledge-focused CompletedThe primary objective of the study focuses on the kinetics of plasma CRP measured during the overall management (before the angioplasty procedure until the discharge of hospitalization) of patients with ST+ ACS requiring emergency transluminal angioplasty.
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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New study checks how much constipation drug gets into breast milk
Knowledge-focused Recruiting nowPrucalopride is a medicine used to treat constipation. The main aim of the study is to measure prucalopride concentrations in breast milk. Other aims are to check the growth and development of babies breastfed by their mothers who took prucalopride and to check if the babies had …
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Can a phone call replace a doctor visit after surgery?
Knowledge-focused CompletedThis study will compare patient reported outcomes (PROs) of patients seen at virtual phone visits compared to in-person visits for 6 weeks, 12 weeks, and 6 months post-operative follow up at a sports medicine clinic. This study will determine if there is a difference in PROs betw…
Sponsor: Jonathan Wu • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Breathing in a new way to see lungs: MRI with tracer gases
Knowledge-focused Stopped earlyThis is a single centre study. The overarching hypothesis of this study is that MRI with inhaled tracer gases can provide high quality images of lung function to complement conventional 1H MRI. The study interventions do not affect the standard of care.
Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:48 UTC