New Frown-Line treatment shows promise in First-Time users
NCT ID NCT05248880
First seen Feb 20, 2026 · Last updated May 15, 2026 · Updated 15 times
Summary
This study tested a new botulinum toxin injection, AGN-151586, for treating moderate to severe frown lines between the eyebrows. About 300 adults who had never used such treatments were randomly assigned to get either the study drug or a placebo. The goal was to see if the treatment safely reduces wrinkle severity at maximum frown after one week.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Clear Dermatology & Aesthetics Center /ID# 238990
Scottsdale, Arizona, 85255-4134, United States
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Clinical Research Center of the Carolinas /ID# 239064
Charleston, South Carolina, 29407, United States
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Clinique D /ID# 239653
Laval, Quebec, H7N 6L2, Canada
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DMR Research PLLC /ID# 239061
Westport, Connecticut, 06880, United States
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DelRicht Research /ID# 244890
Baton Rouge, Louisiana, 70809, United States
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Dr Melinda Gooderham Medicine Profession /ID# 239657
Cobourg, Ontario, K9A 0Z4, Canada
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Duplicate_Austin Institute for Clinical Research /ID# 238989
Pflugerville, Texas, 78660, United States
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Duplicate_Kavali Plastic Surgery and Skin Renewal Center /ID# 244808
Atlanta, Georgia, 30328, United States
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Kalo Clinical Research /ID# 247279
West Valley City, Utah, 84120-2058, United States
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Marcus Medical Spa /ID# 241703
Redondo Beach, California, 90277, United States
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Maryland Dermatology Laser, Skin, & Vein Institute /ID# 239067
Hunt Valley, Maryland, 21030-3216, United States
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Pacific Derm /ID# 239654
Vancouver, British Columbia, V6H 4E1, Canada
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SkinDC /ID# 238988
Arlington, Virginia, 22209, United States
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Steve Yoelin MD Medical Associate Inc /ID# 243197
Newport Beach, California, 92663, United States
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The Centre for Clinical Trials /ID# 245873
Oakville, Ontario, L6J 7W5, Canada
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WDC Cosmetic and Research, PLLC /ID# 233935
Wilmington, North Carolina, 28405, United States
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YVR Aesthetics Training & Study Centre /ID# 241858
Vancouver, British Columbia, V5Z 1H2, Canada
Conditions
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