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This study compares the acute aerobic, metabolic, and threshold-related physiological responses elicited by the 30-15 Intermittent Fitness Test (30-15IFT) and a treadmill-based incremental running test in elite female football players. Using a randomized crossover design, all par…

The goal of this clinical study is to check if obeldesivir (ODV; GS-5245) is safe and well-tolerated by children with respiratory syncytial virus (RSV) infection. It will also look at how well ODV helps reduce the time it takes for children to feel better and for their RSV sympto…

To identify a neural representation of odor identity, it is necessary to dissociate molecular structure from perceptual identity/similarity. Whether the olfactory system employs a coding scheme in which the similarity between neural features is systematically related to perceptu…

The goal of this intervention study is to study the effectiveness of the oral health education module (MyBRUSH) in improving the knowledge, attitude, and behaviour on toothpaste use and toothbrushing among 12-year-old children. This study also aims to study the effectiveness of t…

A placebo controlled, single blind, cross-over study evaluating the short-term effect of oleoylethanolamide (OEA) with LipiSperse supplementation on metabolic pathways in healthy participants.

Setting up a regional (multicentre), longitudinal cohort of people suffering from irritable bowel syndrome followed up in consultation to study the natural history of the disease and its prognosis.

Adaptations to resistance training are highly specific and depend on the combination of external loading and the level of individual adaptability. As the relationship between load and velocity of movement is strong and linear, the application of velocity-based training (VBT) has …

This study will look at how dentists in the UK are using Silver Diamine Fluoride (SDF) in their everyday practice. SDF is a liquid treatment that helps stop tooth decay. It's especially useful for treating children, as it can be applied quickly and without the need for drilling o…

Background: Muscle flexibility is a fundamental physical quality for body development, daily life and sports activities, and also for maintaining muscle quality during aging. Limited flexibility leads to an increased prevalence of musculoskeletal injury in general population and …

The glycemic index (GI) ranks carbohydrate-containing foods based on their effect on postprandial blood glucose levels. Foods or food products with lower GI values (55 or less) are absorbed more slowly, gradually increasing blood glucose and insulin levels. Fruits are believed to…

The goal of this experimental study is to investigate the transdiagnostic role of death anxiety in depression and anxiety symptoms in participants from the general population. The main questions it aims to answer are: 1. Does the mortality salience task induce death anxiety? 2.…

The aim of this study is to examine the effects of digital game addiction on the musculoskeletal system and the reflections of these effects on the quality of life of adults.

The goal of this observational study is to learn about the influence of extracellular water on volume status in adult sepsis patients presenting with hemodynamic instability. The main question it aims to answer is: • Can measurement of extracellular water (MoistureMeterD, Delfin…

The purpose of this study is to determine if, compared to non-depressed adults, differences exist in skin blood flow and sweating responses to passive heat stress in adults with clinically diagnosed depression, those with depression who are prescribed and taking SSRIs and those w…

The goal of this clinical trial is to evaluate the effects of consuming meat and eggs from regenerative/pastured versus conventional farming practices on health biomarkers in middle-aged adults. The main questions it aims to answer are: How does consumption of pastured animal pr…

The aim of this study was to compare knee joint position sense between sitting with visual input and prone without visual input in individuals with and without knee osteoarthritis.

Primary objective： 1. To evaluate the effect of Itraconazole ( CYP3A and P-gp inhibitors) on HMPL-453 pharmacokinetics(PK) in healthy subjects 2. To evaluate the effect of Rifampin (CYP enzyme inducer) on HMPL-453 pharmacokinetics (PK) in healthy subjects Secondary objectives： …

Objectives: The purpose of this study is to examine how meal timing in a one-meal-a-day (OMAD) regimen influences neurocognitive outcomes. Methods: Twelve cognitively active participants (academics, students, software engineers) will complete three randomized OMAD conditions, co…

Nursing students' first clinical practice experiences are one of the most anxiety-inducing and stressful aspects of nursing education. Nursing students experience anxiety due to fear of making mistakes in clinical practice, clinical practice grades, reactions from patients and th…

The foot is a terminal joint that opposes external resistance in the lower kinetic chain. It plays a primary role in weight transfer and ground response between the body and the ground. It plays a role in maintaining an upright posture, lowering the gravitational line against a n…