Depression and heat: new study explores body temperature control

NCT ID NCT06805851

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how adults with depression respond to heat stress compared to those without depression. Researchers will measure skin blood flow, sweating, and core temperature during passive heating. The goal is to understand if depression or antidepressant medications like SSRIs and SNRIs change how the body cools itself.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help explain why some people with depression have trouble regulating body temperature, potentially guiding future treatments.

What could go wrong

This is an early observational study with only 64 participants. It does not test a treatment, so results may not lead to direct medical changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder Heat Stress Disorders major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Noll Laboratory

    RECRUITING

    University Park, Pennsylvania, 16802, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••