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The goal of this clinical trial is to learn if micronized progesterone (PROMETRIUM®) influences the muscle-building response to resistance exercise in healthy premenopausal women aged 18-30 years. The main questions it aims to answer are: 1. Does progesterone change the rate of…

Excessive or problematic smartphone use has become increasingly common and has been associated with various psychological and physical health consequences, including anxiety, depressive symptoms, reduced sleep quality, musculoskeletal pain, and heightened pain perception. Postope…

The objective of this PAS is to demonstrate the continued safety and clinical effectiveness of the Jewel P-WCD.

This study aims to examine the acute effects of an elastic band warm-up on sprinting and vertical jump performance in female football players. A crossover design will be used across three separate sessions: (1) standardized warm-up (WU), (2) warm-up followed by elastic band activ…

This single-center retrospective observational study includes all human milk donors collaborating with the milk bank at České Budějovice Hospital between 2021 and 2025. Using anonymized data extracted from the hospital database, the study will quantify the frequency of donations …

The goal for this clinical trial is to compare acute immune effects of three nutraceutical ingredients and blends to a placebo.

Artificial Intelligence (AI) is transforming scientific research by enabling computers to perform tasks that require human intelligence - such as data analysis, pattern recognition, prediction, and language processing. AI is now integrated into every stage of the research proces…

This cross-sectional study investigated the prevalence of hand joint hypermobility among 400 university students and its relationship with hand grip strength. MCP joint mobility was assessed using a universal goniometer, and grip strength was measured with a hand dynamometer. Par…

TTN is the most common respiratory disorder in the perinatal period, causing 40% of cases of respiratory distress after birth. Lung fluid absorption is initiated by beta-adrenergic agonists, such as endogenous steroids and Catecholamine, which increase during labor. Delayed absor…

The objective of this study is to evaluate the performance and safety of the VCool Intranasal Cooling System in healthy adult volunteers. The study is designed to gather preliminary data regarding air flow rates and time required to reduce core body temperature to 35.5℃ and maint…

Adolescent idiopathic scoliosis (AIS) is a spinal condition that develops during adolescence and often requires long-term conservative treatment, including scoliosis-specific therapeutic exercises. The success of exercise-based treatment largely depends on adolescents' motivation…

This observational, questionnaire-based study aims to evaluate health professionals' perceptions regarding the potential subconscious effects of intraoperative conversations on patients. Although intraoperative awareness is rare, neuroscientific evidence suggests that unconscious…

The aim of the study being to investigate the effects of caffeinated chewing gum on shot put performance

Objective: To evaluate patient satisfaction, postoperative pain, inflammatory re-sponse, and analgesic consumption following All-on-Four implant surgery performed under analgosedation. Methods: This prospective clinical study will include 30 adult patients classified as ASA phys…

To compare the impact of simulation practices using a high-reality simulator, hybrid simulator and task-trainers on tracheal aspiration levels of nursing students' knowledge, skills, satisfaction, and self-confidence.

The goal of this clinical trial is to find out whether the ramp position or sniffing position is better for endo tracheal intubation which provides better hemodynamic stability and short intubation time and good laryngoscopic view in regards of cormack lehane grading.

The investigators propose a multicenter retrospective study to assess clinical, biochemical, and auxological characteristics at diagnosis and during follow-up in a cohort of Caucasian pediatric patients diagnosed with autoimmune hyperthyroidism before puberty. These prepubertal p…

Oral hygiene practices are fundamental to maintaining oral health, preventing dental plaque accumulation, halitosis, stains, gingival and periodontal diseases, and improving overall quality of life. Dental plaque plays a central role in the initiation of caries and periodontal di…

This study aimed to investigate whether static Q angle reflects dynamic landing mechanics in young female athletes.

Both sarcopenic obesity and chronic obstructive pulmonary diseases (COPD) are common conditions that mainly affect middle-aged and older adults. Previous research has shown that increased dietary intake of total and plant-based protein is associated with a lower risk of sarcopeni…