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127005 trials found · Page 5702 of 6351
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Tiny brain waves may tell doctors when preterm babies can go home
Knowledge-focused CompletedLate preterm infants contribute to significant neonatal intensive care unit health care resource utilization because of their sheer numbers. Determinants of the length of hospitalization (LOH) in this population are understudied. Gestational age (GA) is used most commonly as a pr…
Sponsor: Brown University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Breast cancer study reveals how surgery decisions impact emotional Well-Being
Knowledge-focused OngoingThe goal of this research study is to learn more about how different treatment decisions may influence the quality of life in women with breast cancer. Researchers want to use what is learned from this study to help future patients with breast cancer to be more informed when maki…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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New MRI scans aim to unlock secrets of the pancreas in type 1 diabetes
Knowledge-focused By invitation onlyThe overall goal of this research is to develop and validate standard operating procedures (SOP) to assess the human pancreas in individuals with type 1 diabetes (T1D) and other forms of diabetes using advanced, quantitative magnetic resonance imaging (MRI) approaches.
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Blood protein may hold key to depression treatment success
Knowledge-focused CompletedPredictive factors and biomarkers of response to antidepressants in major depressive disorder are scarce. Beta-arrestins are proteins which inhibit G Protein Coupled Receptors and desensitize serotonergic and dopaminergic receptors. The study hypothesis is that Beta-arrestins 1 a…
Phase 4 • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:05 UTC
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Dialysis patients: which imaging technique works best for blocked access?
Knowledge-focused CompletedThe reason the investigators are doing this study is to compare the results of angiography versus angiography with intravascular ultrasound in dialysis grafts/fistulas that are blocked.
Phase 4 • Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Osteopathic touch tested against placebo for back pain relief
Symptom relief CompletedThe purpose of this study is to determine whether a standardised osteopathic manipulative treatment is more effective than a placebo of osteopathic manipulative treatment, in sub-acute and chronic non-specific low back pain on functional recovery at 3 months.
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 26, 2026 13:43 UTC
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New survey aims to put AF Patients' daily struggles into numbers
Knowledge-focused CompletedThis study is aiming to develop a Health Related Quality of Life (HRQoL) scale for patients who have atrial fibrillation (AF).
Sponsor: Barts & The London NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Chemo heart risk under the microscope in lymphoma patients
Knowledge-focused CompletedAll patients enrolled in the study will have to be treated with a chemo immunotherapy scheme R-CHOP with doxorubicin, with doxorubicin analogue or non pegylated liposomal anthracycline (R-COMP; Sec. 648 DM) administered every 21 days for 6 cycles. In unfavourable patients (stage …
Sponsor: Fondazione Italiana Linfomi - ETS • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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DC churches partner with NIH to tackle heart health in black communities
Knowledge-focused Recruiting nowBackground: \- Past studies suggest that the best way to improve heart health in the Black community is through community-based programs. Researchers will partner with DC community leaders. They will collect information about the health and health needs of people in mostly Black…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Brain scans reveal secrets of cognitive decline after injury
Knowledge-focused OngoingThe objective of this exploratory study is to elucidate the underlying cerebral mechanisms of cognitive deficits. To achieve this, the investigator will apply functional brain imaging techniques to patients suffering from cognitive deficits due to cerebral lesions. The investiga…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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New probe could spot hidden leaks after rectal surgery
Diagnosis CompletedThe aim of this study is to monitor by microdialysis the postoperative outcomes in order to identify anastomotic leaks after rectal surgery.
Phase 3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 27, 2026 07:51 UTC
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Scientists uncover hormone clues in obesity and diabetes
Knowledge-focused CompletedThe 26RFa was recently discovered in the hypothalamus. In rodents it seems to be related to glucose metabolism and obesity. However, no data exists in obese patients or in patients with diabetes. Thus, the investigators planned to dose 26RFa level in obese patients before and aft…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Diabetes drug may alter your taste buds and food desires
Knowledge-focused Stopped earlyThis is an open-label comparative study in three parallel groups. It is expected that 90 patients and/or healthy volunteers will participate in this biomedical research. Distribution in groups * 30 patients with type 2 diabetes and an indication for treatment with a GLP1 analog…
Phase 4 • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Decades-Long study aims to unlock secrets of aging
Knowledge-focused Recruiting nowBackground: \- The Baltimore Longitudinal Study of Aging (BLSA) is a clinical research program on human aging that began in 1958. Volunteers of different ages join the study when they are healthy, and have follow-up visits for life. Visits last for multiple days. Participants ar…
Sponsor: National Institute on Aging (NIA) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Could a safer anesthetic help premature babies born by C-Section?
Knowledge-focused CompletedOne of the problems during general anesthesia (GA) for caesarean section is the place of opioid agents. Indeed, the literature does not provide so far a clear answer regarding the use of opioids prior to extraction of the newborn. Indeed, if the opioid administration at induction…
Phase 1/2 • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Blood cancer patients' journeys mapped over a decade
Knowledge-focused Recruiting nowProspective Cohort Study of clinical and laboratory data of patients with hemopathy.
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Massive twin birth study aims to find safest delivery
Knowledge-focused CompletedThe purpose of this study is to determine the best obstetrical practices for twin delivery.
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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7-Year checkup: how radiation affects teeth and gums in cancer survivors
Knowledge-focused CompletedThe current study (ORARAD II) will examine participants of the original cohort for a visit roughly 7 years after the start of RT. The primary outcomes will be the 7-year rate of dental caries, periodontal disease, tooth loss, osteoradionecrosis and salivary flow.
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC
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New study reveals pregnancy risk when starting IUD or implant after unprotected sex
Knowledge-focused CompletedThis project will quantify rates of contraceptive failure when unprotected intercourse occurs 6-14 days prior to initiation of highly effective reversible contraceptives (such as IUD's and Implants).
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Could eye pigment levels predict vision damage in severe nearsightedness?
Knowledge-focused CompletedLutein ans zeaxanthin, carotenoids provided by dietary intake are mainly located in the macular area. Its absorption peak at 460 nm may reduce photic damages. The macular pigment density can be evaluated by its optical density. Reduced macular pigment level is a significant ris…
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC