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116076 trials found · Page 5617 of 5804
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Scientists to scan brains all night to unlock sleep secrets
Knowledge-focused Recruiting nowBackground: An electroencephalogram (EEG) measures the brain s electrical activity. EEG shows that the louder the sound needed to wake a person, the deeper the person s sleep. Researchers are using functional magnetic resonance imaging (fMRI) to study people during sleep so they…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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New drug shows promise for tough bladder cancer?
Disease control CompletedThe purpose of this study is to study the activity and effects of BGJ398 on bladder cancer tumors that are confined to the lining of the bladder.
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Newborn brain map could sharpen seizure detection
Knowledge-focused CompletedThis is a retrospective study based on the images contained in the database of the University Hospital of Amiens. There is no further examination. Electroencephalography (EEG) and Near-Infrared Spectroscopy (NIRS). These sources are widely used to specify the source of certain ev…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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No-Needle brain scans for toddlers tested
Knowledge-focused CompletedThe purpose of this study is to perform brain scans using magnetic resonance imaging (MRI) instrument on children aged 6 months up to 5 year old children. This procedure is usually done with sedation but the study will see if it can be done without sedation.
Sponsor: Arkansas Children's Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Spine treatment data collection ends early
Knowledge-focused TerminatedDetails regarding the degenerative spine disorders will be collected with a specific focus on the use of osteobiologics in treating degenerative conditions and their impact on fusion, as well as patient-reported outcomes for these conditions.
Sponsor: AO Innovation Translation Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Can your therapist find your ribs by touch? study says ultrasound knows better
Knowledge-focused CompletedUltrasound was used to identify the location of a rib. This was compared to a practitioner's ability to palpate the area.
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Neck fractures in seniors: new study reveals hidden bone weakness
Knowledge-focused CompletedUsually, cervical spine fractures are not considered as osteoporotic fractures. However, recent studies show that odontoid fractures are the most common fractures of the cervical spine in elderly and may occur in a context of low trauma energy. Thus, the goal of this observationn…
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Massive tumor study counts rare gene fusions
Knowledge-focused CompletedThis retrospective study has a primary objective to estimate the incidence of NTRK gene fusion depending on the histological diagnosis.
Sponsor: Institut Bergonié • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Brain scans reveal how kids with autism form memories
Knowledge-focused CompletedThe aim of this study is to investigate the neural substrates of associative memory in Autism Spectrum Disorder using both behavioural and EEG assessments.
Phase: NA • Sponsor: University Hospital, Caen • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Tennis elbow treatment showdown ends early
Symptom relief TerminatedThe primary objective of this study is to compare the evolution of pain profiles among patients suffering from lateral epicondyalgia (tennis elbow) following three types of treatment: PRP-L injection versus type A botulinum toxin injection versus corticoid injection.
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Dreaming of better moves: sleep boosts skills learned in your mind
Knowledge-focused CompletedThis study is designed to determine the neural networks underlying the sleep-related motor consolidation process following motor imagery practice. While beneficial effects of sleep are expected for sequential movement but not for adaptation motor tasks, the corresponding neuroana…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:12 UTC
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Heart rate drug may keep arteries young, study suggests
Knowledge-focused CompletedThe conduit arteries exhibit a viscoelastic behavior. Visco-elasticity is partially regulated by endothelium and contributes to the optimization of the heart-vessel coupling. Aging or high resting heart rate (HR) could alter visco-elastic properties leading to increase stiffness …
Phase: PHASE3 • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Experimental drug AR-42 tested on brain tumors – early results uncertain
Disease control TerminatedThis will be a multi-center, proof of concept phase 0 study to assess the suppression of p-AKT in Vestibular Schwannoma (VS) and meningiomas by AR-42 in adult patients undergoing tumor resection. AR-42 is a small molecule which crosses the blood brain barrier (BBB) in rodents, bu…
Phase: EARLY_PHASE1 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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Experimental drug aims to curb disinhibition in dementia patients
Symptom relief TerminatedTreatment of disinhibition syndrome in participants with Neurodegenerative Disorder.
Phase: PHASE2 • Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Tiny study digs into vaccine memory genes
Knowledge-focused CompletedAnalyse the transcriptomic signature of anti vaccinia memory B cells at a short time after vaccination as compared to the signature already established in long-lived memory B cells.
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Scientists induce mild oxygen drop to mimic Alzheimer's symptoms in healthy brains
Knowledge-focused TerminatedThe early assessment of new symptomatic drugs for Alzheimer disease remains difficult because of the lack of predictive end-point. The use of a battery including different parameters could improve this early development. In healthy volunteers, to test the reverse effect of sympto…
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Nationwide study reveals how labor induction methods affect mothers and babies
Knowledge-focused CompletedSince it is a frequent intervention in Obstetrics, labor induction is rarely evaluated from national population-based cohorts. The study aims to assess the frequency of different induction methods used in France from a prospective population-based cohort of women with an induced …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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ICU suction procedure questioned: new study looks at lung effects
Knowledge-focused CompletedLittle is known about the procedure of extubation of patients admitted in Intensive Care Units (ICU). In particular, effects of tracheal suction during extubation have never been evaluated. Tracheal suction induces alveolar derecruitment in sedated patients under mechanical venti…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Blood cancer drug safety checked in small Follow-Up study
Disease control CompletedRollover study supporting hematological disorder indications from Celgene sponsored CC-486 (oral azacitidine) protocols eligible for participation in the study.
Phase: PHASE2 • Sponsor: Celgene • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Liver transplant study aims to predict outcomes by measuring frailty
Knowledge-focused TerminatedIn order to ensure the equity of the liver allocation process, it is important to create objective, scientifically validated markers of frailty in patients with end-stage liver disease that accurately predict patient outcomes. Many measures have been developed to assess this clin…
Sponsor: Baylor Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC