Can MRI and tissue tests predict breast cancer before it starts?

NCT ID NCT03303846

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether combining breast MRI with blood and tissue samples can help find early signs of breast cancer in high-risk women. About 344 women will undergo standard screening MRI and donate leftover tissue and blood. The goal is to better understand how normal breast tissue changes might signal cancer risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to better ways to predict breast cancer risk in high-risk women using imaging and biomarkers.

What could go wrong

This is an observational study, not a treatment trial. It may not directly change patient care or outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

  • Duke University

    Durham, North Carolina, 27705, United States

  • Ohio State University, Stefanie Spielman Comprehensive Breast Center

    Columbus, Ohio, 43212, United States

  • University of Southern California

    Los Angeles, California, 90033, United States

  • University of Wisconsin

    Madison, Wisconsin, 537192, United States