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116076 trials found · Page 5597 of 5804
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New ankle brace aims to fix foot drop after stroke
Symptom relief TerminatedTo assess the benefit of an anti-varus ankle foot orthosis (CALIGALOC, Bauerfeind) on gait and balance parameters in hemiparetic patients.
Phase: NA • Sponsor: University Hospital, Lille • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Mucus-Busting asthma trial fizzles out
Symptom relief TerminatedThis study evaluates 20% n-acetylcysteine (NAC) in the treatment of moderate-to-severe asthma that is complicated by mucus in the airway, as determined by CT imaging. The study is a crossover design, which means that half the study participants will get 20% NAC in the first 14-da…
Phase: PHASE4 • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC
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Dental implant design showdown: which connection wins for healthy gums?
Knowledge-focused CompletedThe complete fill of the inter-implant mucosa is much more challenging between two implants, than single implants, and is considered to be unpredictable (Tymstra et al., 2011). However, previous clinical studies have pointed to a relationship between the inter-implant mucosa fill…
Phase: NA • Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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New scale aims to spot frailty in seniors during routine checkups
Diagnosis TerminatedEvaluate the sensitivity of the GERONTOPOLE scale, used by general practitioners in primary care outpatients for the diagnosis of frailty in non-dependent people more than 65 years old, using as reference the "évaluation gériatrique standardisée clinique" (EGS)
Sponsor: University Hospital, Lille • Aim: Diagnosis
Last updated Jun 27, 2026 12:37 UTC
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Lab study explores how JAK inhibitors affect immune cells in arthritis
Knowledge-focused TerminatedThis study will investigate whether inhibitors of the JAK / STAT signaling pathway can increase anti-inflammatory functions of B cells in patients with RA using in vitro and in vivo experiments.
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Fortified bread may help control blood sugar and boost metabolism
Knowledge-focused CompletedWheat and wheat derived products are highly consumed around the world. They constitute the major dietary source of protein and energy for many individuals. Wheat contains moderate quantity of low quality protein lacking in some essential amino acids, primarily lysine, thus wheat …
Phase: NA • Sponsor: American University of Beirut Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Tiny study tests MRI-Guided radiation for tough prostate cancers
Knowledge-focused CompletedThis small study will investigate the feasibility of using multi-parametric MRI to introduce and support adaptive radiotherapy treatments for high-risk prostate cancer.
Sponsor: East and North Hertfordshire NHS Trust • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:51 UTC
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Military study seeks blood clues to Sleep-Pain mystery after surgery
Knowledge-focused CompletedThis is an observational, prospective study that will leverage existing Standard of Care (SOC) patient reported outcomes (PRO) and Electronic Medical Record (EMR) data and collect additional Pain Rating Scale (PRS) data and blood samples from patients who consent to be in the stu…
Sponsor: Defense and Veterans Center for Integrative Pain Management • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Nurse training boosts injection skills, study finds
Knowledge-focused CompletedThe aim of this study is to observe how many nurses perform the steps of creating an air lock, identifying the ventrogluteal site, and applying the Z-track technique in intramuscular injections after theoretical and practical training. Research Hypotheses * The rate of administ…
Phase: NA • Sponsor: Nazike Duruk • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:30 UTC
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Military pain study seeks 300 volunteers to donate data and samples
Knowledge-focused Recruiting nowThis Pain Registry Biobank is a prospective cohort design study whereby data (PASTOR survey, blood and saliva specimens, clinical data) is collected from participants in a longitudinal fashion with continual enrollment.
Sponsor: Defense and Veterans Center for Integrative Pain Management • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Salt sensitivity secrets revealed in small study
Knowledge-focused CompletedThis study aims to assess the salt sensitive blood pressure response to dietary salt load compared with radiological markers of salt handling.
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Can video games fix your shoulder pain?
Symptom relief TerminatedThe objective of this study is to assess the interest and the efficiency of virtual reality in functional rehabilitation of shoulder pain and shoulder injuries. Participants will follow a 12-week rehabilitation program based either on exercises or on a program integrating virtual…
Phase: NA • Sponsor: University of Liege • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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New breathing tube trick may make surgery safer for obese patients
Knowledge-focused CompletedVentilation, as well as intubation of a morbidly obese patient, is challenging and require special preparations and skilful hands, in this study laryngeal mask airway insertion is used as a bridge for intubation to facilitate ventilation as give enough time to anaesthetics and mu…
Phase: NA • Sponsor: Suez Canal University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Hidden vitamin c shortages found in nursing homes?
Knowledge-focused CompletedThe clinical finding of skin rashes which appear after a vitamin C deficiency in Long Term Care Unit leads us to believe that the institutional diet could predispose to this kind of deficiency. Vitamin C has a key role into the struggle against oxidant stress and is involved into…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:39 UTC
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Parkinson's drug side effect targeted by antioxidant NAC – but trial stalls
Symptom relief TerminatedImpulse control disorders encountered in Parkinson's disease (PD) are induced by dopaminergic medications and their frequency is estimated to be nearly 20%, mainly under dopaminergic agonists (AD).
Phase: PHASE3 • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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Ear zaps may reveal nerve secrets
Knowledge-focused TerminatedWhile invasive vagal stimulation has proven its therapeutic effectiveness over the past 20 years, particularly in the treatment of epilepsy or depression, its implementation is hampered by the high cost, high technicality and sometimes significant side effects. Non-invasive vagal…
Phase: NA • Sponsor: Hôpital Européen Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Chloride pills tested for heart failure fluid control
Knowledge-focused CompletedThis study is designed to investigate the quantitative effects of sodium-free chloride supplementation on electrolyte balance, volume status, and sodium avidity in stable heart failure patients in a highly controlled environment.
Phase: EARLY_PHASE1 • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:07 UTC
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Could a mouthpiece tame a heart rhythm disorder?
Disease control TerminatedThis pilot study is expected to determine the efficacy of using the midline traction designed MyTAP plus mouth shield (MyTAP + MS) oral appliance combination in decreasing the number of Atrial Fibrillation events. The MS is a patient comfort accessory to the MyTAP.
Phase: NA • Sponsor: Texas A&M University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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C-Section bleeding study: does tranexamic acid help clotting?
Knowledge-focused CompletedThe aim of the study is to evaluate haemostasis and fibrinolysis in peripartum of caesarean delivery and the effect of tranexamic acid (TXA) given in prevention of post-partum haemorrhage (PPH).
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Chilean study checks if psychological distress survey works in spanish
Knowledge-focused CompletedAIM: study the psychometric properties of the Spanish version of the Clinical Outcomes in Routine Evaluation-Outcome Measure (CORE-OM), an instrument that measures psychological distress, in the Chilean population. SAMPLES: two clinical samples (1. outpatients from three psychot…
Sponsor: Pontificia Universidad Catolica de Chile • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC