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116076 trials found · Page 5588 of 5804
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Could a simple arm cuff replace the need for an artery needle during surgery?
Knowledge-focused CompletedTo compare a noninvasive and continuous radial artery blood pressure measurements utilizing ViTrack (developed by Dynocardia) to the standard of care radial artery catheterization, in patients undergoing surgery or those who are being cared for in the intensive care unit
Phase: NA • Sponsor: University of Massachusetts, Worcester • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:25 UTC
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Fat infusion study aims to unlock diabetes clues
Knowledge-focused CompletedThe primary goal of this study is to determine the dose of fatty acids that acutely induces mild insulin resistance in healthy volunteers. We hypothesize that a low-dose of fatty acid infusion (Intralipid/heparin) will cause a mild insulin resistance. The dose of fatty acid infus…
Phase: EARLY_PHASE1 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Ear surgery head tilt may squeeze brain, eye test reveals
Knowledge-focused CompletedStudies exist to determine the effect of laparoscopic surgical procedures on increased intra-abdominal pressure; these studies include optic nerve sheath diameter (ONSD) measurement in various positions such as trendelenburg and prone, and the effect of the laryngoscope used in i…
Phase: NA • Sponsor: Bursa Yuksek Ihtisas Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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300 patients studied to uncover hidden causes of fluid in the lungs
Knowledge-focused CompletedPleural effusion is a common clinical condition characterized by the accumulation of excess fluid within the pleural space due to disruption of normal pleural fluid dynamics. The etiology is diverse and includes systemic conditions such as congestive heart failure, liver cirrhosi…
Sponsor: Mansoura University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Scientists hunt for clues to pregnancy complications in blood and placenta
Knowledge-focused Recruiting nowCollect blood pressure, blood, amniotic fluid, placenta and other samples from normal pregnant women, patients with pregnancy-induced hypertension and those who have experienced miscarriage, and conduct tests on them.
Sponsor: Second Affiliated Hospital of Wenzhou Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Eye rubbing habits linked to uneven keratoconus severity
Knowledge-focused CompletedObservational study comparing patients with inter-eye asymmetric keratoconus with patients with inter-eye symmetric keratoconus.
Sponsor: Centre Hospitalier Régional Metz-Thionville • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Massive biobank launches to unlock secrets of major diseases
Knowledge-focused Recruiting nowCU-Med Biobank collaborates with different researchers for collecting and distributing human biospecimens and clinical data for assisting scientific research.
Sponsor: Chinese University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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5,000 healthy volunteers help scientists map the Body's hidden ecosystem
Knowledge-focused Recruiting nowBacterial and fungal microbiota will be different between individual body sites; however, particular microbiome profiles both whole-body and site-specific will be unique to volunteers with a given parameter such as medical diagnosis, diet, medications taken, geographical area; et…
Sponsor: University Hospitals Cleveland Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Heart rate tracking could speed up colon surgery recovery
Knowledge-focused Recruiting nowHRV measurement of patients recovering from laparoscopic colorectal resection for any pathology.
Phase: NA • Sponsor: Joint Authority for Päijät-Häme Social and Health Care • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Heart failure and AF: new clues from inflammation and genes?
Knowledge-focused Completedthe goal of this case-control cross-sectional study is assessing in a cohort of patients with CHF and permanent AF * The serum levels of some candidate cytokine variables and their relationship with some selected metabolic variables and some echocardiographic variables. * the ex…
Sponsor: University of Palermo • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:12 UTC
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New study tracks how patients heal after pelvic fractures
Knowledge-focused Recruiting nowThe purpose of this study is to understand the trajectory of function and self-reported outcomes of patients following pelvic and acetabular, treated both operatively and nonoperatively.
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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AI's influence on doctor decisions under the microscope
Knowledge-focused CompletedThe study is one part of a "bundle" of experiments that constitute Project Three of a National Eye Institute grant. Project Three includes a series of experiments that investigate how changing the input from a simulated AI can affect the decisions made by human observers in a two…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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New drug EI1071 tested for safety in healthy people
Knowledge-focused CompletedThis was a first-in-human study to determine the safety, tolerability, and pharmacokinetics of EI1071 after single and multiple doses in healthy volunteers.
Phase: PHASE1 • Sponsor: Elixiron Immunotherapeutics Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Smart devices track cancer recovery at home
Knowledge-focused CompletedThis study examines at-home monitoring of patient-generated phsyiologic health data and patient-reported outcomes. Patient-generated health data using at-home monitoring devices and smart device applications are used more and more to measure value and quality in cancer care. This…
Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Recovery room delays: what holds up discharge after surgery?
Knowledge-focused OngoingThis is a retrospective chart review to determine the etiologies contributing to prolonged PACU discharge at a major Orthopedic Ambulatory Center
Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Study on adding albumin to diuretics for cirrhosis fluid retention halted early
Disease control TerminatedA common complication of the progression of cirrhosis is fluid retention (ascites, edema, or pleural effusion). Loop diuretics are the treatment of choice for fluid retention in cirrhotic patients; however, many of these patients demonstrate diuretic resistance, requiring higher …
Phase: PHASE4 • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Jun 26, 2026 18:16 UTC
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2000 volunteers needed to test Next-Gen MRI scans
Knowledge-focused Recruiting nowPatients and healthy volunteers will be scanned in order to test new sequences.
Phase: PHASE4 • Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Breathing easy? study probes daily life with respiratory failure
Knowledge-focused Recruiting nowTo determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it.
Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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New monitoring methods tested for haemophilia b treatment
Knowledge-focused CompletedThe purpose of this study is to evaluate the performance of different methods for measuring factor IX activity levels in haemophilia B patients treated with eftrenonacog-alfa and assess its pharmacodynamics (PD) in a real-life setting.
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Nano-X rotation study for cancer patients ends early
Knowledge-focused TerminatedPatients will complete validated psychometric questionnaires to quantify their experience of being rotated at different speeds using the Nano-X patient rotation system.
Phase: NA • Sponsor: University of Sydney • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC