Gut bacteria may control fat production in obese teens

NCT ID NCT03454828

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how gut bacteria might influence metabolism in 38 teenagers, some with obesity and some lean. Participants ate special diets while researchers measured short-chain fatty acids and fat production in the liver. The goal was to understand if gut bacteria play a role in obesity-related metabolic problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
carbohydrate-controlled diet
What this could lead to
If successful, this could help explain how gut bacteria influence weight and metabolism in young people, pointing toward new diet or treatment strategies.
What could go wrong
This is a small, completed observational study with only 38 participants, so results may not apply to everyone. It does not test a treatment, so no direct health benefits are expected.

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Conditions

The condition(s) this trial relates to.

obesity disorder Pediatric Obesity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Research Unit

    New Haven, Connecticut, 06520, United States

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