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127005 trials found · Page 5554 of 6351
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Fingerprick test for blood thinners put to the test
Diagnosis CompletedThis study is to evaluate the INR levels in patients taking phenprocoumon using the LumiraDx Point of Care INR test and comparing the results to the laboratory reference method , the ACL Elite Pro. Comparison will also be made with the Roche Coaguchek point of care INR test (poin…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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Tiny coil placed inside nose could help surgeons spot hidden brain tumors
Knowledge-focused Recruiting nowTumors of the pituitary gland comprise up to 20% of all brain tumors. The central location and the small size of the pituitary gland make the management of tumors particularly challenging. Transsphenoidal surgery (TSS) to resect pituitary tumors is highly successful at achieving …
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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ER sedation gets a tech upgrade: Computer-Controlled propofol tested
Symptom relief CompletedProcedural sedation is an emergency medicine technique that provides a brief, deep sedation in order to perform very painful emergency emergent procedures such as displaced fracture or dislocated joints reduction. Propofol is recommended for this purpose, injected administered in…
Phase 4 • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Double nerve block may cut opioid use after lung surgery
Symptom relief CompletedMonocentric, randomized, controlled, single-blind study who's aim is to demonstrate the efficacy of the association of paravertebral block and serratus plane block with paravertebral block alone
Phase 4 • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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New laser device could revolutionize eye disease detection
Knowledge-focused Recruiting nowThis study investigates a new technology to assess the structure and function inside the eye. Retinal imaging of subjects with inner and outer retinal defects to detect areas of abnormal structure and function compared to other visual function tests.
Sponsor: Randy Kardon • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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Scientists launch national effort to unravel mysteries of rare blood disorder
Knowledge-focused Recruiting nowUnexplained chronic hypereosinophilia (HE) and hypereosinophilic syndromes (HES) are heterogeneous regarding the organ involvements (heart, lungs, skin, .. or none), the evolutionary profiles, the response to treatments. Underlying mechanisms are largely unknown and may associat…
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Scoliosis study aims to uncover hidden physical deficits in adults
Knowledge-focused Recruiting nowAdults with scoliosis have not been the focus of much research in physical therapy despite their prevalence being very important. Adults with idiopathic scoliosis have a reported prevalence of about 2-11%. This includes adolescents with idiopathic scoliosis who have become adults…
Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Could dissociation play a role in obesity?
Knowledge-focused CompletedTHe aim of this study is to determine the frequency of dissociative tendencies in the obese population treated at the CELIOBE (Liberal Center for Obesity Support) at Hôpital Privé La Louvière among patients consulting for the first time and looking for a medical or surgical cours…
Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Knee implant study seeks best surgical alignment
Knowledge-focused CompletedThe purpose of this study is to compare migration patterns between mechanical and anatomic alignment surgical techniques for the Attune S+ CR-FB knee system using model-based RSA over the first 2 post-operative years.
Sponsor: Canadian Radiostereometric Analysis Network • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Study reveals artery stiffness from common cancer drug
Knowledge-focused CompletedAntiangiogenic treatments are used in many tumor locations such as metastatic colorectal cancer (mCRC) with a significant improvement in carcinological results on overall survival and / or progression-free survival. However, their use is characterized by an increase in side effec…
Phase 4 • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Liver fat during pregnancy may signal future diabetes risk
Knowledge-focused OngoingThe aim of this study is to utilise ultrasound, using an established method for detecting NAFLD, to determine whether the presence of NAFLD in women with GDM, detected during routine scanning, is a marker of deterioration in glycaemic status post-partum. We propose to assess the …
Sponsor: University Hospitals of North Midlands NHS Trust • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Camera pill reveals gut nerve secrets in Parkinson's
Knowledge-focused By invitation onlyThe goal of this research is to determine (1) the feasibility of tethered capsule OCT esophageal imaging in the Parkinson's Disease population; (2) the morphologic changes in the enteric nervous system of the esophagus in patients with Parkinson's disease.
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Could a brain hormone fix low sex hormones? small study hints at possibility
Knowledge-focused CompletedThe goal of this study is to develop novel treatments for patients with a condition called hypogonadotropic hypogonadism (HH) through the use of exogenous kisspeptin.
Phase 2 • Sponsor: Stephanie B. Seminara, MD • Aim: Knowledge-focused
Last updated Aug 28, 2026 00:00 UTC
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Heart risk after chemo: scientists hunt for clues in your blood
Knowledge-focused Recruiting nowThis study evaluates why some cancer patients but not others experience changes in heart function following treatment with chemotherapy.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC
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New device could spot failed pain blocks during mastectomy
Knowledge-focused CompletedParavertebral Block (PVB) combined with general anesthesia (GA) is a conventional pain treatment for breast surgery but sometimes failures can occurs. The efficacy of this block has to be evaluated. Also, for the intra-operative analgesic evaluation of this block, it is necessary…
Sponsor: Institut de Cancérologie de Lorraine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Botox for groin pain? small study explores new treatment
Symptom relief Stopped earlyPubalgia is a pain syndrome located in the groin area. This syndrome is mainly described in young male athletes and typically affect the superficial muscles defining the boundaries of the femoral triangle, i.e. gracilis, pectineus, adductor brevis and especially adductor longus, …
Phase 2 • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Brain zapping trial for Schizophrenia's 'Negative Symptoms' ends early
Symptom relief Stopped earlyThe main purpose of this study is to learn how transcranial magnetic stimulation (TMS) helps improve negative symptoms of schizophrenia. These 'negative symptoms' include anhedonia (the inability to enjoy things), low motivation, and decreased facial expression. TMS is a noninva…
Sponsor: Beth Israel Deaconess Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Mom's weight before pregnancy linked to Baby's growth and food preferences?
Knowledge-focused Recruiting nowThe goal of this observational study is to investigate the concentrations of leptin, insulin, liver expressed antimicrobial peptide 2 (LEAP2), and cortisol in plasma and breast milk and their relationship with eating behavior, growth, adiposity and with the levels of these hormon…
Sponsor: Instituto de Desarrollo e Investigaciones Pediátricas Prof. Dr. Fernando E. Viteri • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Could a cystic fibrosis drug ease stubborn sinus infections?
Symptom relief Recruiting nowThe purpose of this pilot study is to explore wither ivacaftor in refractory CRS patients will demonstrate safety and tolerability; restore CFTR-mediated Cl- secretions as measured by EDSPD testing; produce detectable improvements in validated measures of CRS including the SNOT-2…
Early phase 1 • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Scientists dive deep into colorectal tissue to uncover cancer clues
Knowledge-focused Recruiting nowThe primary objective of COLON-IM is to describe colorectal tissue microenvironment (neutrophils infiltrate) of patients with benign or malignant colorectal lesion (from stage I to III according to Tumor Node Metastasis (TNM)/ Union for International Cancer Control (UICC) classif…
Sponsor: Centre Leon Berard • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC