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116076 trials found · Page 5518 of 5804
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Pupil dilation may reveal secrets of hearing nerve
Knowledge-focused ENROLLING_BY_INVITATIONThe research team will evaluate pupillary dilation from vagal nerve stimulation of Arnold's Nerve, a branch of the vagus nerve, during routine cochlear implantation surgery.
Phase: NA • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Dental implant study tests new connector to save bone and gums
Knowledge-focused TerminatedIn dental implant restoration, available literature demonstrates the advantage of using tall abutments, with a change of diameter with respect to the implant and a conical internal connection in the abutment-implant gap. However, for multiple restorations, the abutment-prosthesis…
Phase: NA • Sponsor: Universidad de Granada • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Liver study tracks antibiotic levels in Fluid-Filled bellies
Knowledge-focused CompletedThe investigators designed an observational multicenter explorative in vivo study to investigate the changes in ceftriaxone pharmacokinetics in blood and ascites. The investigators will include a total of 20 patients with liver cirrhosis admitted to the ward of participating hosp…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Knee replacement patients: do your pain catheters stay put?
Knowledge-focused OngoingThe goal of this observational study is to determine the incidence of dislodgement for adductor canal catheters after total knee arthroplasty on post-operative day 1. We will also attempt to identify factors associated with secondary catheter failure.
Sponsor: Sunnybrook Health Sciences Centre • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:29 UTC
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Which wire shape moves teeth faster? study compares round vs rectangular archwires
Knowledge-focused CompletedPatients at the Orthodontic Department of the University of Damascus Dental School will be examined, and subjects who meet the inclusion criteria will be included. Then, initial diagnostic records (diagnostic gypsum models, internal and external oral photographs, and radiographic…
Phase: NA • Sponsor: Damascus University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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New MRI scan could reveal hidden acidity in prostate tumors
Knowledge-focused OngoingThis is a single site, prospective pilot study to determine the feasibility and safety of the administration of HP 13C bicarbonate in 10 patients with prostate cancer to determine potential hydrogen (pH) values in surrounding tissue. The proposed study will evaluate pre-surgical …
Phase: EARLY_PHASE1 • Sponsor: Robert Flavell, MD, PhD • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Eye fluid analysis may unlock secrets of rare eye condition
Knowledge-focused OngoingDetermination of proteins and their levels in the vitreous of eyes with or without pseudoexfoliation syndrome (PEX)
Phase: NA • Sponsor: Prim. Prof. Dr. Oliver Findl, MBA • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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New ultrasound software could simplify fatty liver diagnosis
Diagnosis CompletedNon-alcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease, with an estimated prevalence of 5-30% in the general population and 55-80% in patients with type 2 diabetes. Methods for the quantitative and non-invasive assessment of liver fat conten…
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC
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New device maps cervix stiffness to predict preterm birth risk
Knowledge-focused CompletedThe assessment of cervical stiffness plays a major role in obstetrics, for example to assess the risk of preterm birth. The Pregnolia System is a CE-certified measuring device that objectively determines cervical stiffness using a slight negative pressure. The Pregnolia System w…
Sponsor: Pregnolia AG • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Wrist surgery showdown: big cut vs tiny scope – which is better?
Knowledge-focused TerminatedPerilunate injuries can be debilitating injuries that involve the carpus. These can limit patients' functionality both acutely and long-term. Not only do their potential for nerve injury increase risk of lasting weakness and chronic pain, but their complex surrounding involving t…
Phase: NA • Sponsor: Emory University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Sugar-Cutting advice put to the test in UK study
Knowledge-focused CompletedThis randomised controlled trial aims to assess the effects of three different types of dietary advice for reducing free sugar intakes, on intakes of free sugar, in a sample of the UK population.
Phase: NA • Sponsor: Bournemouth University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Can a nasal air device calm Asthma's hidden nerve stress?
Knowledge-focused CompletedThe project will be pursued in our respiratory, autonomic nervous system physiology laboratory (Respiratory, autonomic nervous system physiology laboratory, Department of Pneumology and Intensive Care Medicine, RWTH Aachen University Hospital). Overactivity of the sympathetic ne…
Sponsor: RWTH Aachen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Bone graft study: immune reactions under the microscope
Knowledge-focused CompletedThis study evaluates the occurrence of anti-human leukocyte antigen (anti-HLA) antibodies following bone regeneration procedures performed prior to dental implant therapy. Allogeneic bone grafts are widely used in regenerative oral surgery due to their favorable osteoconductive a…
Phase: NA • Sponsor: Medical Innovation Center Wroclaw • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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HELLP syndrome blood markers tracked daily in new study
Knowledge-focused CompletedProspective observational study about progression and regression of biological parameters of HELLP syndrome
Sponsor: CHU Mohammed VI Marrakech • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Survey reveals hidden toll of irregular periods on Women's lives
Knowledge-focused CompletedAmong the causes of ovulation disorders (group II of anovulation according to the World Health Organization classification), the dominant one is polycystic ovary syndrome (PCOS), and the remaining cases are classified as Hypothalamic-Pituitary-Ovarian Axis Dysfunction (HPOD). The…
Sponsor: Jagiellonian University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Scientists zap brains to map connections
Knowledge-focused Recruiting nowThe purpose of the proposed study is to broaden our understanding on the neural effects of High Definition Transcranial Direct Current Stimulation (HD-tDCS) so that its clinical effects can be further improved.
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Tiny study tracks why vets skip or stick with Post-Stroke arm exercises
Knowledge-focused CompletedResearch shows that exercising at home can improve arm and hand movement after a stroke. Unfortunately, it can be hard to exercise enough to make a difference in arm and hand movement after stroke. In this study, the investigators will try to determine things that make it easy or…
Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Altitude alters sleep test results, study finds
Knowledge-focused CompletedThe purpose of this study is to investigate the effect of short-term descent in healthy residents at moderate altitude (\>1000 m.a.s.l.).
Phase: NA • Sponsor: Tsogyal Latshang • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Spinal zap fails to prove brain benefit in rare stroke complication
Knowledge-focused TerminatedCerebral vasospasm is characterized by a vasoconstriction of cerebral arteries causing a reduction of cerebral blood flow (CBF) and leading to ischemia and infarction of the brain parenchyma. Cerebral vasospasm is a serious complication of aneurysmal subarachnoid hemorrhage (SAH)…
Phase: NA • Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Cheaper prosthetic foot put to the test in small study
Knowledge-focused CompletedThe goal of this observational study is to evaluate and compare the performance of two prosthetic feet for unilateral transtibial amputees during both indoor and outdoor activities. The main research questions aim to answer are: 1. Can a low-cost prosthetic foot enhance gait mec…
Sponsor: The Hong Kong Polytechnic University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:57 UTC