Gene clues could personalize Crohn's treatment

NCT ID NCT07263477

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at whether differences in the IL-7 receptor gene are linked to the risk of developing Crohn's disease and how well patients respond to the drug infliximab. Researchers analyzed genetic samples from 303 Crohn's patients and 514 healthy people. The goal is to better understand who might benefit most from this treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

infliximab

What this could lead to

If successful, this could help identify which Crohn's patients are more likely to benefit from infliximab, enabling more personalized treatment.

What could go wrong

This is a retrospective, observational study, not a controlled trial. The findings are preliminary and need confirmation in larger, prospective studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • the Second Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325000, China