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127005 trials found · Page 5442 of 6351
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Real-World chemotherapy patterns in advanced pancreatic cancer revealed
Knowledge-focused CompletedThe study objectives are to find out: 1) palliative chemotherapy patterns and prognosis in patients with locally advanced or metastatic pancreatic cancer in Korea's real clinical settings, and 2) reasons adopted by clinicians in choosing therapeutic drugs.
Sponsor: Boryung Pharmaceutical Co., Ltd • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:16 UTC
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Hearing aid study explores link between better hearing and brain health
Knowledge-focused Recruiting nowThe primary objective of the study is to evaluate OID hearing intervention on cognition among patients who could vs. do utilize an OID. We will also evaluate the long-term effects of OID use on secondary outcomes measures (hearing performance, quality-of-life, social interaction,…
Sponsor: University of South Florida • Aim: Knowledge-focused
Last updated Sep 10, 2026 09:00 UTC
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New shoulder surgery spares muscles, aims for faster recovery
Symptom relief By invitation onlyThe investigators purpose of this study are to perform a prospective clinical study to determine the following after subscapularis-sparing anatomic total shoulder arthroplasty performed for glenohumeral osteoarthritis: 1. patient-reported outcomes 2. shoulder motion and strength…
Sponsor: University of Utah • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Can Self-Compassion help you sleep? new study tests mindfulness against standard insomnia treatment
Symptom relief CompletedThe main aim of this study is to test the efficacy of a Compassive Acceptance Intervention protocol (developed by the research team) for Chronic Insomnia in comparison with the standard treatment (CBT-I).
Sponsor: University of Coimbra • Aim: Symptom relief
Last updated Jun 26, 2026 13:56 UTC
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Algerian study reveals hidden toll of COVID-19 on diabetic patients
Knowledge-focused CompletedDiabetes is a major risk factor for severe COVID-19 and poor clinical outcomes during hospitalization. However, little is known about the medium- and long-term metabolic consequences of COVID-19 in people with diabetes after hospital discharge. The DMD-COV study is a prospective…
Sponsor: Algerian Society of Diabetology • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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New rule could keep kids with cancer out of the hospital during fever
Symptom relief Stopped earlyFebrile neutropenia (NF) is the leading cause of unscheduled hospitalization in children with cancer. Management classically involves emergency admission to hospital for intravenous antibiotic treatment until resolution of fever and neutropenia. However, children with NF are a he…
Sponsor: University Hospital, Lille • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Pertussis booster study: does your first vaccine matter?
Knowledge-focused CompletedPrimary Objectives : * To describe the long-term humoral immune responses to pertussis, diphtheria, and tetanus after homologous and heterologous pertussis vaccine priming regimens * To determine the effects of the priming regimen on humoral responses to booster vaccination with…
Phase 4 • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:25 UTC
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Dye test could help surgeons spot shoulder Re-Tear risk during surgery
Knowledge-focused CompletedRotator cuff re-tear is a common delayed complication of arthroscopic rotator cuff repair. This process of re-tear is multifactorial and there has not been any readily identifiable perioperative measure that is predictive of subsequent rotator cuff failure. There have been no hum…
Phase 1 • Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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New study monitors Aimovig's safety in pregnant women with migraine
Knowledge-focused Recruiting nowThe primary objective of this study is to estimate the proportion of major congenital malformations in infants of women with migraine exposed to erenumab-aooe during pregnancy compared to infants of women with migraine unexposed to erenumeb-aooe.
Sponsor: Amgen • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Healing at a distance: reiki tested for myeloma patients
Symptom relief CompletedThis research study is being done to determine if Distance Reiki therapy offers a quality of life benefit, and improves immunity compared to patients receiving Sham Distance Reiki therapy or no additional Reiki intervention.
Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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New app aims to cut surgery drug mistakes in simulated trial
Knowledge-focused CompletedThe goal of this study is to compare the usability of a novel, medication-related clinical decision support (CDS) application to the current standard medication administration and documentation workflow. The study will occur in a simulation setting, using a manikin and test patie…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Liver cancer study halted after just 2 patients
Disease control Stopped earlyThe primary goal of this study is to gather efficacy data concerning the progression-free survival rate with electromagnetic fields plus Regorafenib when compared to historical data with Regorafenib alone as a second-line therapy in patients with advanced hepatocellular carcinoma…
Phase 2 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Robot brain surgery accuracy put to the test
Knowledge-focused CompletedThe purpose of this study is to evaluate the accuracy of the Neurolocate recording system of the neurosurgical robot Neuromate, marketed by Renishaw, in order to optimize surgical procedures, costs and patient comfort.
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New anchor shows promise in rotator cuff surgery study
Disease control CompletedThis study evaluates the safety of the HEALICOIL Knotless Suture Anchors in patients requiring a repair of the rotator cuff tendon repair
Sponsor: Smith & Nephew, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New PET tracer aims to reveal hidden immune activity in tumors and arteries
Diagnosis Stopped earlyPhase II study to evaluate the clinical potential of 68GaNOTA-anti-MMR-VHH2 for in vivo imaging of Macrophage Mannose Receptor (MMR)-expressing Macrophages by means of Positron Emission Tomography (PET) in patients with oncological lesions in need of non-surgical therapy, patient…
Phase 2 • Sponsor: Universitair Ziekenhuis Brussel • Aim: Diagnosis
Last updated Jun 27, 2026 13:00 UTC
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Massive study investigates cancer risk of popular diabetes drug
Knowledge-focused CompletedThe aim of this study is to evaluate whether exposure to semaglutide influences the risk of pancreatic cancer in patients with type 2 diabetes. This is achieved by estimating the risk of pancreatic cancer associated with semaglutide use as compared to use of other non-incretin an…
Sponsor: Novo Nordisk A/S • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Steroid injection during fibroid procedure may ease Post-Op pain
Symptom relief CompletedThe purpose of this research is to investigate if administration steroids (anti-inflammatory medication) via the uterine arteries during uterine fibroid embolization (A non surgical procedure for treating uterine fibroids by blocking their blood supply) can help reduce the pain, …
Phase 3 • Sponsor: University of Miami • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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E-Ink screens in ERs could boost patient satisfaction
Symptom relief CompletedCommunication with patients on their clinical status is important in delivering care in the emergency department. During times of high volume or complex patients, there may be lapses in communicating with patients about their hospital course or plans of action. These miscommunica…
Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated Jul 19, 2026 00:00 UTC
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Could a caregiver-given brain zap at home prevent falls in seniors?
Symptom relief OngoingIn this project, the investigators propose to demonstrate the feasibility of remotely-monitored, caregiver (or spouse)-administered, home-based tES (transcranial electrical stimulation) intervention to improve mobility in ambulatory older adults with recent falls. This is a four-…
Sponsor: Hebrew SeniorLife • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Could a melt tablet replace IV sedation for eye surgery?
Symptom relief CompletedThis study is designed to explore the sedative and analgesic effectiveness of the Midazolam/Ketamine melt compared to IV sedation in subjects undergoing intraocular surgery.
Sponsor: Vance Thompson Vision • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC