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127005 trials found · Page 5441 of 6351
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Eyelid Surgery's Long-Term effects on dark circles revealed
Knowledge-focused CompletedThis observational study aims to investigate the long-term outcomes of transconjunctival lower eyelid blepharoplasty, with a specific focus on changes in lower eyelid hyperpigmentation or hypopigmentation and morphological alterations of wrinkles at short-term and long-term posto…
Sponsor: Peking Union Medical College • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Hidden gaps in labor pain care: study investigates whether insurance status affects C-Section pain relief
Knowledge-focused OngoingThe Agency for Healthcare Research and Quality (AHRQ) defines a disparity as a difference or a gap that exist between two groups, which is both statistically significant, larger than 10%, and indicates poor quality for the minority (non-referent) group. Despite advances in public…
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Video call or Face-to-Face? study tests which genetic counselling works best
Knowledge-focused Recruiting nowThis study aims to compare clinical outcomes (informed choice and genetic counselling outcomes) and cost (provider and patient time, travel, and telehealth platform) between telegenetics and in-person genetic counselling.
Sponsor: National Cancer Centre, Singapore • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Hip bone clues could help doctors time scoliosis treatment better
Knowledge-focused CompletedThis study aims to explore the use of proximal femoral head for the assessment of skeletal maturity in patients with idiopathic scoliosis. The aim is to validate the use of the stages of proximal femoral epiphyseal closure in assessing pubertal growth landmarks in this patient co…
Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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National audit reveals gaps in cervical cancer care across india
Knowledge-focused Recruiting nowThis is a combination of retrospective and prospective observational study that will be performed across NCG and other participating centers to report compliance to chemoradiation for cervical cancer. This audit will include patients treated with standard of care treatment, in th…
Sponsor: Tata Memorial Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Could a mother's virus raise her baby's heart defect risk? new study investigates.
Knowledge-focused CompletedBeyond EV-B, there are clinical observations to implicate other viruses in birth defects, including CHD. Since the Rubella epidemic of 1960s', however, viruses have received little attention and certainly no comprehensive study, especially using next generation sequencing (NGS), …
Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Can we better predict surgery risks for GI cancer patients?
Knowledge-focused CompletedAccurate prediction of postoperative morbidity and mortality is essential for optimizing perioperative management in patients undergoing gastrointestinal cancer surgery. This study evaluates the predictive performance of commonly used perioperative risk scoring systems in patient…
Sponsor: Lütfi Kırdar City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Shock relief? nerve zaps may ease irritable bowel symptoms
Symptom relief Stopped earlyTo discuss the effects of improving the irritable bowel syndrome patients' quality of life and defecation after implementing acupuncture-like Transcutaneous Electrical nerve stimulation.
Sponsor: National Taipei University of Nursing and Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Diet advice for expecting moms: a small study on weight control
Knowledge-focused CompletedA high percentage of women are either overweight or obese before pregnancy and many women are exceeding the gestational weight gain recommendations when pregnant. Excessive gestational weight gain increases the risk of maternal and fetal complications. To help with this, women ne…
Sponsor: University of Nicosia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New group therapy aims to help people with anxiety face the unknown
Symptom relief CompletedGeneralized anxiety disorder (GAD) is a debilitating condition involving excessive and uncontrollable worry and anxiety. Difficulty tolerating the uncertainties of life, known as intolerance of uncertainty (IU), has been shown to be key in the development and maintenance of GAD s…
Sponsor: University of Manitoba • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
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Massive data dive: could old gout drugs shield against Alzheimer's?
Knowledge-focused CompletedThis study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the same indication.
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Zapping the brain to boost focus: new study tests a 20-Minute attention hack
Knowledge-focused CompletedBackground: Visuospatial attention enables individuals to detect and process relevant stimuli efficiently. The posterior parietal cortex (PPC), a core hub of the dorsal attention network, exerts top-down control over visual scanning and is closely linked to alpha-band oscillation…
Sponsor: Medipol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Simple shoulder stretches after heart device surgery may improve Long-Term arm function
Symptom relief CompletedShoulder dysfunction frequently occurs after cardiac implantable electronic device (CIED) implantation, adversely affecting quality of life. While early postoperative exercise is known to be effective in the short term, data on long-term durability is limited. This 3-year longitu…
Sponsor: Erzincan Binali Yildirim Universitesi • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Scientists scan brains of cocaine users to uncover dopamine secrets
Knowledge-focused Recruiting nowThis study uses \[11C\]NPA positron emission tomography (PET) and a d-amphetamine challenge to image amphetamine induced dopamine release in the striatum in subjects with cocaine use disorders (CUD). Amphetamine-induced dopamine release data from this study will be correlated wit…
Early phase 1 • Sponsor: Rajesh Narendran • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Which ACL surgery is safer for kids? new study compares techniques
Knowledge-focused CompletedThis cohort study compares to groups of patients with reconstruction of anterior cruciate ligament (ACL). Patients in group 1 had ACL-reconstruction in the years 2001-2010 with a transphyseal drilling technique. Patient in group 2 had ACL-reconstruction in the years 2013-2018 wit…
Sponsor: Aarhus University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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New blood tests could simplify Wilson's disease monitoring
Knowledge-focused CompletedSerum exchangeable copper (EC) and relative exchangeable copper (REC) are blood tests developed to improve the assessment of copper levels in patients with Wilson's disease. EC measures the fraction of copper in the blood that is not bound to ceruloplasmin and reflects copper acc…
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Lying face down: a simple trick to help COVID-19 lungs?
Knowledge-focused CompletedThe proposed study will be conducted to investigate the mechanism of patients' responses to prone positioning with coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS) and non-COVID-19 ARDS utilizing lung ultrasound.
Sponsor: Rush University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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New study tracks pelvic changes after radiation in women with pelvic cancer
Knowledge-focused OngoingThis study investigates changes in physical measures of pelvic health and patient-reported outcomes of sexual function, intimate relationship, and quality of life over time in women undergoing radiation therapy for pelvic cancer. Evaluating vaginal changes prior to and after a co…
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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New hip implant tracked for 10 years – will it last?
Knowledge-focused OngoingThis study titled "Prospective, Multicentre Study to Assess Performance of the MonoCer Acetabular Cup in Primary Total Hip Replacement" is a multi-centre prospective registry-nested cohort study, using AOANJRR's web-based data collection system integrated with Registry data colle…
Sponsor: Medacta International SA • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Real-World chemotherapy patterns in advanced pancreatic cancer revealed
Knowledge-focused CompletedThe study objectives are to find out: 1) palliative chemotherapy patterns and prognosis in patients with locally advanced or metastatic pancreatic cancer in Korea's real clinical settings, and 2) reasons adopted by clinicians in choosing therapeutic drugs.
Sponsor: Boryung Pharmaceutical Co., Ltd • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:16 UTC