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127005 trials found · Page 5410 of 6351
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New study aims to boost cancer screening among american indians
Knowledge-focused CompletedThere are continued disparities in cancer incidence, mortality, and survival between American Indians (AIs) and Whites on cancers responsive to early screening (i.e., breast, colorectal, and cervical) in the US. In New Mexico (NM), AIs compared with other racial/ethnic population…
Sponsor: New Mexico Cancer Research Alliance • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Lung disease drug tested in rare muscle condition – trial cut short
Disease control Stopped earlyThere is likely a role for using anti-fibrotic medications in patients with myositis-associated interstitial lung disease (MA-ILD) to slow down disease progression, especially in patients who have fibrotic and progressive disease. These patients however are currently being exclud…
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated Jun 26, 2026 13:17 UTC
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Teacher coaching program aims to curb classroom bullying
Knowledge-focused CompletedThe investigators' overall objective is to demonstrate the efficacy of the Bullying Classroom Check-Up (BCCU) on elementary aged students' aggressive and bullying behaviors, teacher practices, and student and teacher relationships. The investigators' principal hypothesis is that …
Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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New Light-Based technique reveals corneal strength in real time
Knowledge-focused By invitation onlyThe objective of this study is to measure the Brillouin biomechanical properties in keratoconic corneas and characterize biomechanical alterations that occur after corneal procedures that inherently strengthen or weaken the cornea by evaluating the change in Brillouin metrics bef…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Could Low-Nicotine smokes plus E-Cigs cut harm for mentally ill smokers?
Knowledge-focused CompletedThis study aims to determine the health effects of very low nicotine content in cigarettes, in conjunction with the availability of nicotine-containing electronic cigarettes (e-cigs) among smokers with mental health conditions (SMHC).
Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:59 UTC
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Sleep loss may worsen heart health and social bias in african americans
Knowledge-focused CompletedThis study aims to to test effects of sleep loss on perceived discrimination and cardiovascular functioning as well as identify moderators of the racial discrimination and objective sleep link in a sample of 80 African Americans.
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Herbal combo shows promise for diabetes control in small study
Disease control CompletedType 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by persistent hyperglycemia, which contributes to the formation of advanced glycation end-products (AGEs) and increases the risk of long-term complications. Bitter melon (Momordica charantia L.) contain…
Sponsor: Universitas Muhammadiyah Surakarta • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Shocking strength: EMS workout tested on couch potato women
Knowledge-focused CompletedAbstract Aim of the Study: This study aimed to compare the effects of Electro Muscle Stimulation (EMS) exercise on physical performance in sedentary women. Methods: Our study was conducted with a total of 27 sedentary women, 12 EMS, and 15 controls, aged 19-24 years. The tests a…
Sponsor: Ondokuz Mayıs University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Scientists track ewing sarcoma cases to learn what works best
Knowledge-focused Recruiting nowObservational prospective trial aimed to collect the collect demographic, clinical, surgical, pathological and molecular characteristics and treatment from patients affected by skeletal Ewing Sarcoma
Sponsor: Italian Sarcoma Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Heart failure patients may benefit from drug optimization clinic after defibrillator implant
Disease control CompletedGuideline-directed medical therapy (GDMT) and the mortality benefit it provides in the heart failure with reduced ejection fraction (HFrEF) population are well-established by multiple professional society guidelines. GDMT refers to initial medical therapy with angiotensin-convert…
Sponsor: Ratika Parkash • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Massive malawi study could reshape HIV care worldwide
Knowledge-focused OngoingTo achieve global goals for the treatment of HIV, many countries are piloting and scaling up differentiated service delivery models (DSD). A handful of efforts have been formally described and evaluated in the literature; many others are being implemented formally or informally u…
Sponsor: Boston University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Gout patients in the south get a new tool: storytelling on a tablet
Disease control OngoingThe prevalence of gout has been steadily increasing over several decades and is correlated with the rising burden of obesity, chronic cardiac and renal disease; all conditions overrepresented in the Southeastern U.S. - particularly in African Americans. Through a novel emergency …
Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 12:31 UTC
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Smart insoles could forecast knee surgery success
Knowledge-focused Recruiting nowThis multicenter prospective observational study aims to evaluate whether preoperative clinical variables and wearable sensor-derived gait features can predict postoperative improvement after total knee arthroplasty (TKA). Participants will undergo standardized gait assessments u…
Sponsor: Yonsei University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:14 UTC
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Experimental heart drug pulled before first patient enrolled
Disease control CancelledTransthyretin is a protein produced in the liver that transports thyroid hormone and vitamin A. A single substitution of an amino acid in the structure of TTR can result in a relatively unstable protein, the breakdown products of which (predominantly monomers) aggregate abnormall…
Phase 2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Spinal deformity study seeks to unlock best value care
Knowledge-focused OngoingThe study will examine if variability in created value (outcome/costs) over the care cycle for ASD patients can be explained by patient and treatment characteristics.
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC
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Can a special MRI scan predict who will have another stroke?
Knowledge-focused CompletedIntracranial atherosclerotic disease (ICAD) is one of the most important causes of ischemic stroke and is also associated with some recurrent stroke. Safety and effective treatment of ICAD is an important precondition to improve the prognosis of patients. The current therapy for …
Sponsor: Shanghai East Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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AI teaches doctors to see inside the body
Knowledge-focused By invitation onlyPoint-of care-ultrasonography has the potential to transform healthcare delivery through its diagnostic and therapeutic utility. Its use has become more widespread across a variety of clinical settings as more investigations have demonstrated its impact on patient care. This incl…
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Needle-Free jet injection matches cream for pain relief in clubfoot babies
Symptom relief CompletedInfants undergoing Ponseti treatment for idiopathic clubfoot often require percutaneous tendoachilles lengthening (TAL) after serial casting. This procedure is frequently performed in the office with a local anesthetic to avoid exposure to general anesthesia in the operating room…
Phase 4 • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can video visits help older cancer patients? new study tests Tele-Geriatric care
Symptom relief OngoingThe purpose of this study is to find out if a telemedicine program for older adults in cancer treatment is a practical way to understand and meet these participants' unique needs. Telemedicine is the use of secure video technology on a desktop computer, laptop, smartphone, or tab…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated Jul 11, 2026 00:00 UTC
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Scientists probe cellular signals that may trigger early labor
Knowledge-focused CompletedThis completed observational study evaluated the expression of Hippo-YAP pathway-related genes and proteins and selected microRNAs in maternal blood, placental tissue, and myometrial tissue obtained from women who underwent cesarean delivery at term or preterm gestational ages. …
Sponsor: Cumhuriyet University • Aim: Knowledge-focused
Last updated Jul 12, 2026 00:00 UTC