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116076 trials found · Page 5225 of 5804
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Pandemic flu in pregnancy: what happens to mom and baby?
Knowledge-focused CompletedThe purpose of this study is to measure the incidence of A/H1N1 Influenza infection in the mother and her child and to identify the determinants in pregnant women during pandemic period in three public maternities in Paris, France.
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Saltwater IV may boost exercise in POTS patients
Symptom relief OngoingThe investigators will test whether an intravenous infusion of saline (salt water) will improve the exercise capacity in patients with postural tachycardia syndrome (POTS).
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Brain scans reveal how OCD therapy rewires the mind
Knowledge-focused CompletedObsessive compulsive Disorder (OCD) is a frequent psychiatric disorder. Obsessions and compulsions are the two manifestations of this disease. Obsessions are recurrent anxious ideas, and compulsions repetitive behavior aiming to decrease this anxiety. OCD symptoms have been asso…
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:21 UTC
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Hospital team and alerts aim to reduce complications in starved kids
Knowledge-focused CompletedThis cluster-randomized trial will evaluate the impact of a multifaceted intervention (including electronic medical alerts) coordinated by a Nutritional Support Team, on adherence to recommended practices for care of starved children, among health personnel of a large university …
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Can your diet boost your chances of getting pregnant?
Knowledge-focused CompletedThis case-control multicentric study involving fertile and infertile couples aims at evaluating the impact on conception rate of nutritional parameters (biologic, clinic, anthropometric, and food questionnaire).
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Scientists probe why gastric bypass causes dangerous blood sugar drops
Knowledge-focused Recruiting nowRYGB (roux-en-y gastric bypass) has been reported to reverse type 2 diabetes (T2DM) immediately after surgery before any significant weight loss. In addition, a growing number of patients have been recognized with life-threatening hyperinsulinemic hypoglycemia several years follo…
Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:36 UTC
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Can vaginal estrogen be safe for breast cancer survivors? new study investigates
Knowledge-focused CompletedThe purpose of this study is to see if Vagifem® 10mcg is safe for women who have had breast cancer. Vagifem is an estrogen product. It is a tiny tablet that is inserted into the vagina. It relieves vaginal dryness. Women who have had breast cancer are usually told not to take est…
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Tapping away cravings: EFT tested on Hard-to-Quit smokers
Symptom relief Recruiting nowThe National Health Service (NHS) stop smoking service at the Central Lancashire NHS Trust serves a diverse population of smokers, with a very good quit rate and high standards. However, clinical experience predicts that some clients are unlikely to succeed through the NHS smokin…
Phase: EARLY_PHASE1 • Sponsor: Soul Medicine Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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NIH scientists probe immune secrets behind flu vaccines
Knowledge-focused CompletedBackground: \- Seasonal influenza is a major health problem whose impact is typically reduced by vaccination. The H1N1 (swine flu) influenza virus is an emerging pathogen that has the potential to cause devastating illness and even death in the coming months. Currently, there ar…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Scientists launch largest U.S. registry to unravel broken heart syndrome
Knowledge-focused Recruiting nowTakotsubo syndrome is a condition which mimics acute myocardial infarction, and is diagnosed in 1.5% to 2.2% of patients referred to hospital with suspected acute coronary syndrome. It is also known as broken heart syndrome, takotsubo cardiomyopathy, stress cardiomyopathy and api…
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Can a simple amino acid drink help elderly COPD patients keep muscle?
Knowledge-focused CompletedWeight loss commonly occurs in patients with chronic obstructive pulmonary disease (COPD), negatively influencing their quality of life, treatment response and survival. Loss of muscle protein is generally a central component of weight loss in COPD patients. Attempts to reverse m…
Phase: NA • Sponsor: Texas A&M University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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New device may reduce bruising after heart procedure
Symptom relief CompletedIs the FemoSeal® closure device safer and more comfortable than manual compression for femoral artery access closure after coronary angiography?
Phase: PHASE4 • Sponsor: Aarhus University Hospital Skejby • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Can ectoin sprays and drops soothe hay fever? new study investigates
Symptom relief CompletedThe primary objective of this study is to assess the relative efficacy of Ectoin® Allergy Eye Drops and Ectoine® Allergy Nasal Spray compared to placebo, by evaluating Total Nasal Symptom Score (TNSS) and Total Ocular Symptom Score (TOSS). The secondary objectives are : * To ev…
Phase: NA • Sponsor: Bitop AG • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Building a biobank to unlock radiation Therapy's secrets
Knowledge-focused Recruiting nowRATIONALE: Collecting and storing samples of tissue from patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting tissue samples from patients with cancer undergoing radiation therapy. Healthy participa…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Does the flu shot work in IBD patients on immune drugs?
Knowledge-focused CompletedThe primary purpose of the study is to compare the efficacy and safety of influenza vaccine in patients with inflammatory bowel disease (IBD) receiving immunosuppressive therapy with patients not receiving immunosuppressants . The main objective of the study is to evaluate the h…
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Pompe disease study aims to unlock immune secrets for better treatment
Knowledge-focused Recruiting nowThis is a longitudinal natural history study of Infantile Pompe disease. The investigators will regularly collect and review medical information regarding the diagnosis of Pompe disease, response to enzyme replacement (ERT) using alglucosidase alfa (Lumizyme/Myozyme) and response…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Can a blood test spot hidden heart strain during breast cancer surgery?
Knowledge-focused CompletedThe cardiotoxicity of anthracyclines chemotherapy remains a major problem, despite clinical and echocardiographic monitoring. In the case of treatment for breast cancer, surgery requiring general anesthesia may follow chemotherapy. Although a possible interaction between general …
Phase: NA • Sponsor: Institut Bergonié • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Heart attack may leave hidden marks on the brain
Knowledge-focused CompletedThe general purpose of the present pathophysiological study is to investigate the relation between cognitive impairment observed after an acute coronary syndrome and the presence of cerebral anatomo-functional abnormalities. This study will improve the investigators' understandin…
Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Flu shot mystery: why some seniors keep antibodies longer
Knowledge-focused CompletedLittle is known about factors associated with maintenance of hemagglutinin inhibition (HAI) antibodies after influenza vaccination in older adults so the investigators enrolled adults ≥50 years.
Sponsor: Vanderbilt University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC
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Botox vs. painkiller: which eases muscle pain better?
Symptom relief CompletedIn this research prilocaine and botulinum toxin (BoNT-A) interventions prospectively compared to find out the effect of BoNT-A injection on myofascial pain syndrome (MPS). The main question it aims to answer is: Does Botulinum Toxin Type-A an Effective Way of Relieving Pain in M…
Phase: NA • Sponsor: Bursa City Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC