New drug TIN816 tested for sepsis kidney damage
NCT ID NCT05507437
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested an experimental drug called TIN816 in 20 adults in the intensive care unit who had kidney injury from sepsis. The main goal was to learn how the drug behaves in the body and whether it is safe. This was an early-stage study, so it focused on gathering information rather than proving the drug works.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Novartis Investigative Site
Genk, 3600, Belgium
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Novartis Investigative Site
Ottignies, 1340, Belgium
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Novartis Investigative Site
Strasbourg, 67091, France
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Novartis Investigative Site
Toulouse, 31054, France
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Novartis Investigative Site
Kiel, 24105, Germany
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Novartis Investigative Site
Debrecen, 4032, Hungary
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Novartis Investigative Site
Valencia, 46026, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Gut microbes may hold clues to sepsis organ injury
- Scientists hunt for clues to kidney damage in sepsis
- Kidney injury prediction study for sick kids withdrawn before starting
- New arm cuff technique aims to shield kidneys during septic shock
- Can a simple drug help predict kidney trouble in sepsis?
- Experimental enzyme shot aims to rescue kidneys in sepsis patients