Can a simple drug help predict kidney trouble in sepsis?
NCT ID NCT05939245
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study from Indonesia University looked at 40 ICU patients with sepsis-related acute kidney injury. Researchers compared those who received the diuretic furosemide to a control group, measuring a protein called pNGAL in the blood as a marker of kidney damage. The goal was to see if early use of furosemide could help predict or improve kidney outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- furosemide
- What this could lead to
- If successful, this could help doctors predict and manage kidney injury in sepsis patients more effectively.
- What could go wrong
- This is a small, early-stage study (40 participants) that measures a biomarker, not a direct treatment outcome. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Rumah Sakit Cipto Mangunkusumo
Jakarta Pusat, DKI Jakarta, 10430, Indonesia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Gut microbes may hold clues to sepsis organ injury
- Scientists hunt for clues to kidney damage in sepsis
- Kidney injury prediction study for sick kids withdrawn before starting
- New arm cuff technique aims to shield kidneys during septic shock
- New drug TIN816 tested for sepsis kidney damage
- Experimental enzyme shot aims to rescue kidneys in sepsis patients