New antibiotic shows promise for scrub typhus fever
NCT ID NCT07513103
First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 3 times
Summary
This study tested whether the antibiotic tigecycline works better than the standard drug doxycycline for scrub typhus, a bacterial infection spread by mites. Thirty-one hospitalized patients were randomly assigned to receive either tigecycline or doxycycline. Researchers measured how quickly fever went away and tracked any side effects to see if tigecycline is a safe and effective alternative.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tigecycline (compared to doxycycline)
- What this could lead to
- If tigecycline works better, it could offer a new treatment option for scrub typhus, potentially reducing fever faster.
- What could go wrong
- This is a small, completed study with only 31 participants, so results may not apply broadly. Tigecycline may cause side effects or not be more effective than the standard drug.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dankuk university hospital
Cheonan, Chungcheongnam-do, 31116, South Korea
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Gyeonsang National University Hospital
Jinju, 52727, South Korea
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Inha university hospital
Incheon, 22332, South Korea
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