New antibiotic shows promise for scrub typhus fever
NCT ID NCT07513103
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether the antibiotic tigecycline works better than the standard drug doxycycline for scrub typhus, a bacterial infection spread by mites. Thirty-one hospitalized patients were randomly assigned to receive either tigecycline or doxycycline. Researchers measured how quickly fever went away and tracked any side effects to see if tigecycline is a safe and effective alternative.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tigecycline (compared to doxycycline)
What this could lead to
If tigecycline works better, it could offer a new treatment option for scrub typhus, potentially reducing fever faster.
What could go wrong
This is a small, completed study with only 31 participants, so results may not apply broadly. Tigecycline may cause side effects or not be more effective than the standard drug.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Dankuk university hospital
Cheonan, Chungcheongnam-do, 31116, South Korea
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Gyeonsang National University Hospital
Jinju, 52727, South Korea
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Inha university hospital
Incheon, 22332, South Korea