Can a video game rewire the brain to ease PTSD?
NCT ID NCT05313334
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This pilot study tested a digital training task called GAMBIT in 50 adults with PTSD. The goal was to see if playing this brain-training game could improve brain circuit flexibility and reduce PTSD symptoms. The study was terminated early, so the findings are limited.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- GAMBIT Task (a digital inhibitory control training game)
- What this could lead to
- If successful, this could point toward a new, non-drug approach to help people with PTSD by training their brain's control circuits.
- What could go wrong
- This was a very small, early pilot study that was terminated before completion, so results are limited and may not be reliable. The intervention is a simple computer task, not a proven treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
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