Can a video game rewire the brain to ease PTSD?

NCT ID NCT05313334

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study tested a digital training task called GAMBIT in 50 adults with PTSD. The goal was to see if playing this brain-training game could improve brain circuit flexibility and reduce PTSD symptoms. The study was terminated early, so the findings are limited.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
GAMBIT Task (a digital inhibitory control training game)
What this could lead to
If successful, this could point toward a new, non-drug approach to help people with PTSD by training their brain's control circuits.
What could go wrong
This was a very small, early pilot study that was terminated before completion, so results are limited and may not be reliable. The intervention is a simple computer task, not a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

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