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127005 trials found · Page 5209 of 6351
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New study tracks rare muscle disease to pave way for future treatments
Knowledge-focused Recruiting nowThis is a longitudinal study in a cohort of patients with a genetic diagnosis of Primary Mitochondrial Myopathy to describe the natural history of the disease and identify clinical, biochemical, molecular, and radiological variables that allow evaluation of the severity and progr…
Sponsor: Cristina Domínguez González • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:07 UTC
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Rewiring motherhood: brain study targets opioid recovery in new moms
Knowledge-focused Recruiting nowOpioid use disorder (OUD) remains a major public health problem particularly for mothers in the perinatal period, for whom stress, relapse rates, and risk for overdose are elevated. The perinatal period is characterized by significant neural reorganization that determines outcome…
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Zap your insomnia away? small study tests brain stimulation
Symptom relief CompletedThis study is designed to evaluate the efficacy and to explore the best individualized stimulus paradigm of transcranial Electrical Stimulation for insomnia patients.
Sponsor: Shanghai Mental Health Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Which score saves lives? new study tests REMS vs NEWS2 for sepsis
Knowledge-focused CompletedProspective observational study to determine the utility of Rapid Emergency Medicine Score (REMS) in comparison to National Early Warning Score2 (NEWS2) for predicting morbidity and mortality among patients presenting to the Emergency Department with clinical suspicion of Sepsis
Sponsor: Jubilee Mission Medical College and Research Institute • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:08 UTC
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App attack on obesity: can your phone help you lose weight?
Disease control Recruiting nowThe purpose of this study is to determine the effectiveness of mobile health applications in improving health outcomes in patients with overweight and obesity. This study will involve a 6-month long commitment where participants will be expected to use an mHealth app daily, weigh…
Sponsor: San Diego State University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Nightshift sleep breakthrough? study tests CBT for shift work disorder
Knowledge-focused Recruiting nowThe purpose of this project is to test sleep reactivity as an independent cause of Shift Work Disorder (SWD). The primary hypothesis is that those with high sleep reactivity will show persistent SWD symptoms after experimental reduction of circadian misalignment, which will then …
Sponsor: Henry Ford Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Numbing shots could ease mysterious belly pain
Symptom relief Recruiting nowThis is a prospective cohort study of outpatient adults with chronic abdominal wall pain receiving abdominal wall injections, as part of their usual care, with lidocaine. Subjects will be recruited at the outpatient gastroenterology clinic at OHSU.
Phase 4 • Sponsor: Oregon Health and Science University • Aim: Symptom relief
Last updated Jun 26, 2026 13:08 UTC
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Which nerve block is best for hip replacement pain?
Symptom relief CompletedThe hip joint is the largest and one of the most stable joints in the human body. It bears the majority of the body's weight during both dynamic and static activities, making it highly susceptible to degenerative diseases, particularly in the elderly population. In advanced cases…
Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Blood test may predict sepsis survival in ICU
Knowledge-focused CompletedThis retrospective observational study evaluates the prognostic value of the C-reactive protein-albumin-lymphocyte (CALLY) index in adult patients with sepsis admitted to the intensive care unit (ICU). The CALLY index reflects inflammatory, nutritional, and immunologic status and…
Sponsor: Ankara University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Gene clue to Kids' stomach bugs revealed
Knowledge-focused Completedstudy aimed to identify the role of TLR9 (rs352140) gene in suppressing or promoting the inflammation related to H. pylori infection in children.This cross-sectional study was conducted on 50 children with positive H. pylori infection and 50 age and sex matched, negative H. pylor…
Sponsor: Benha University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Longer breathing tube after surgery may cut risks for sleep apnea patients
Knowledge-focused By invitation onlyThis study aims to investigate the effect of prolonged tracheal intubation removal on the incidenceof postoperative complications in patients with gastric cancer complicated with severe obstructive sleepapnea.
Sponsor: Qilu Hospital of Shandong University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Simple blood test may spot newborns at risk for lung trouble
Diagnosis CompletedThis trial is intended to assess the serum levels of interleukin-6 as a predictive factor for the occurrence of meconium aspiration syndrome in infants born with MSAF.
Sponsor: Benha University • Aim: Diagnosis
Last updated Jun 27, 2026 09:02 UTC
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New hip stem holds promise for patients with wide thigh bones
Disease control CompletedTotal hip arthroplasty (THA) is a widely accepted procedure for the treatment of end-stage hip osteoarthritis. Neck preserving short stems have gained popularity in recent years, as they aim to preserve proximal femoral bone stock and enable a more physiological load transfer. Ho…
Sponsor: Krankenhaus Barmherzige Schwestern Linz • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Back pain breakthrough? study seeks clues to who benefits from nerve scar treatment
Knowledge-focused OngoingChronic lumbar radicular pain is a frequently encountered condition that can cause marked pain, limited physical function, and a substantial decline in quality of life. For patients whose symptoms do not respond adequately to conservative treatment, caudal epidural adhesiolysis i…
Sponsor: Mersin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Simple exercises may improve balance and health in diabetic nerve damage
Symptom relief CompletedThe aim of the study is to investigate the effects of modified otago exercises on joint position sense, balance and physical fitness parameters in individuals with diabetic neuropathy. In addition aim of to examine the effects of exercise on metabolic variables and to gain exerci…
Sponsor: Karamanoğlu Mehmetbey University • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Can better sleep and more movement protect memory in seniors?
Knowledge-focused Recruiting nowAssisted living residents who have sleep disturbances are at great risk of developing cognitive impairments. The identification of factors that increase sleep problems in this population is the first step towards improving sleep disorders and reducing and/or delaying the occurren…
Sponsor: University of Calgary • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Simple drug may cut bleeding in broken leg surgery
Disease control CompletedPerioperative blood loss is one of the most frequently encountered and significant complications of spine surgery. Intraoperative and post-operative bleeding cause various complications and negatively affect patient outcomes. There are a range of methods that can be employed to b…
Sponsor: Kathmandu University School of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC
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Virtual reality goggles may ease student nurse jitters
Symptom relief CompletedThis study will examine the effects of brief immersive virtual reality (IVR) exposure (10-15 minutes) using commercially available applications (Beat Saber, TRIPP) on nursing students' clinical anxiety, stress, and adaptation, compared with usual clinical preparation in a control…
Sponsor: Gümüşhane Universıty • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New nursing strategy aims to cut ICU infections
Disease control CompletedThis study aims to evaluate the impact of a multidisciplinary collaborative bundle nursing intervention based on targeted surveillance on the incidence of ICU device-associated infections (DAIs). The control group received routine nursing care, while the intervention group implem…
Sponsor: The First Hospital of Qinhuangdao • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Heart bypass breakthrough? new imaging may boost graft success
Knowledge-focused Recruiting nowThe goal of this observational study is to learn about the long-term effects of Quantitative Flow Reserve (QFR) assessment in patients undergoing Coronary Artery Bypass Grafting (CABG). The main question it aims to answer is: Does preoperative QFR measurement improve graft outco…
Sponsor: Peking University Third Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC