Simple drug may cut bleeding in broken leg surgery
NCT ID NCT07625709
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at whether giving tranexamic acid before surgery can reduce blood loss in people with broken thigh or shin bones. Fifty-four patients received either the drug or a placebo before their operation. Researchers measured blood loss during and after surgery, as well as changes in hemoglobin levels and transfusion needs.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tranexamic acid
What this could lead to
If it works, this could show that a single dose of tranexamic acid before surgery reduces bleeding and the need for blood transfusions in patients with leg fractures.
What could go wrong
This is a small, completed study with only 54 participants, so results may not apply to everyone. There is also a risk of side effects like blood clots or allergic reactions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Dhulikhel Hospital, Kathmandu University Hospital
Dhulikhel, Bagmati, 45200, Nepal