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127005 trials found · Page 5201 of 6351
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Blood vs. tissue: which gum fix works best?
Disease control Recruiting nowTo correct gum recession, patient's own tissue from the roof of the mouth is harvested and placed where there is root exposed. This is considered gold standard of treatment. Sometimes patient don't want to have second surgical site in their mouth and at the same time do not want …
Sponsor: Tufts University • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Breathing exercises and brain games may slow Alzheimer's risk, study suggests
Knowledge-focused CompletedIn the current study, we will examine how daily paced breathing affects plasma amyloid beta levels and the rate of learning in older adults. Healthy adults aged 50-70 who meet all eligibility criteria will be invited to this study. Participants will be randomly assigned to one of…
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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ADHD meds may curb binge eating in kids, tiny study suggests
Symptom relief CompletedLoss of control eating (LOC-E) in youth predicts the later development of full syndrome eating disorders, such as binge-eating disorder (BED), and therefore, could be a relevant target for prevention interventions. Children with attention deficit/hyperactivity disorder (ADHD) are…
Sponsor: Nova Scotia Health Authority • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New study pits ultrasound against laparoscopy for Post-Surgery pain control
Symptom relief CompletedThis prospective, randomized, double-blind study aimed to compare the effects of ultrasound-guided versus laparoscopy-guided transversus abdominis plane(TAP) block on postoperative analgesia in patients undergoing laparoscopic upper abdominal surgery under general anesthesia. Pos…
Sponsor: Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New study asks: do all struggling newborns need breathing machines?
Symptom relief OngoingThe primary aim of this research project is to determine if term neonates (37:0 to 41:6 weeks' gestational age) with mild respiratory distress can safely transition without continuous positive airway pressure (CPAP). The secondary aim is to determine the incidence of pneumothorax…
Early phase 1 • Sponsor: Hackensack Meridian Health • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Laser vs scalpel: which biopsy hurts less for mouth disease?
Knowledge-focused CompletedOral biopsy is essential for diagnosing mucosal lesions such as oral lichen planus (OLP). Laser surgery offers a minimally invasive alternative to traditional techniques, but thermal effects may impact healing and postoperative comfort. The aim of this study was to compare the de…
Sponsor: Catholic University of the Sacred Heart • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Simple signs and amplifiers may cut hospital delirium
Knowledge-focused CompletedThe goal of this observational study is to learn about sensory loss in hospital patients with delirium. The main questions it aims to answer are: * Are hearing and vision loss related to increased risk of having delirium? * Do hearing and vision loss contribute to more severe de…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Can long-acting shots keep schizophrenia symptoms away? new study investigates.
Knowledge-focused CompletedThis prospective longitudinal cohort study will follow patients with schizophrenia who are treated with second generation long-acting injectable antipsychotic medications (LAIs) for 48 weeks to determine the risk of psychotic symptom relapse when treatment adherence is establishe…
Sponsor: Centre for Addiction and Mental Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Can melatonin fix sleep problems in autism? new study investigates brain waves
Knowledge-focused OngoingSleep disturbances and sensory sensitivities are common disabling features of autism, but their underlying causes are not clear. We hypothesize that both of these difficulties reflect disrupted communication between a deep brain structure, the thalamus, and the brain's outer laye…
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Can a prostate implant ease urinary problems during cancer radiation?
Symptom relief CompletedConfirming safety of combining UroLift System prior to SAbR for patients with newly diagnosed prostate cancer and a history of BPH, by measuring the acute complication rate of UroLift System implant in patients with BPH undergoing SAbR (within 90 days of treatment completion)
Sponsor: University of Texas Southwestern Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Vacuum dressing may cut infection risk after emergency abdominal surgery
Disease control CompletedThe study aims to evaluate the efficacy of negative pressure wound therapy (NPWT) compared with primary closure (PC) in surgical site infection (SSI) prevention for laparotomy for peritonitis.
Sponsor: Medical University of Gdansk • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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New numbing cocktail may ease pain of central line insertion
Symptom relief CompletedThe goal of this clinical trial is to find out whether WALANT is an alternative local anesthesia method that can increase patient comfort and reduce pain during CVC procedure, which is one of the invasive procedures to be performed especially in areas where bleeding control is di…
Sponsor: Ataturk University • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Herbal mouthwash takes on chlorhexidine in gum disease showdown
Disease control CompletedThis research was performed to find out the clinical efficacy and the anti-plaque and anti-gingivitis properties of a new oral health product (mouthwash and oral gel; StellaLife) compared to chlorhexidine. This is important since Chlorhexidine (CHX) has side effects, like it alte…
Phase 4 • Sponsor: Stony Brook University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Lollipop could replace painful throat swabs for kids
Diagnosis PausedThis study will enroll children ages 5-17 who test positive for Group A Streptococcus (GAS) at a single clinic visit lasting approximately 30-60 minutes. The primary aim of this study is to assess the accuracy and feasibility of the CandyCollect platform to capture and detect GAS…
Sponsor: University of Wisconsin, Madison • Aim: Diagnosis
Last updated Jun 27, 2026 12:06 UTC
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Brain fog in fibromyalgia: new study probes the link
Knowledge-focused Recruiting nowThe aim of the study is to investigate the relationship between central sensitization parameters and cognitive dysfunction in patients with fibromyalgia.The main questions it aims to answer are: Do central sensitization symptoms affect cognitive dysfunction in patients with fibr…
Sponsor: Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:50 UTC
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Migraine drug safety in pregnancy under scrutiny
Knowledge-focused Recruiting nowMigraine is a common neurological disorder typically characterized by attacks of throbbing or pulsating headache on one side of the head of moderate to severe pain intensity. The purpose of this study is to evaluate fetal, maternal, and infant outcomes through 12 months of age am…
Sponsor: AbbVie • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New study tests faster abortion method for women with scarred uterus
Disease control CompletedThe goal of this clinical trial is to compare the induction-to-abortion time interval between women receiving Laminaria tent followed by misoprostol and those receiving misoprostol alone for mid-trimester abortion induction in women with a scarred uterus. The main question it aim…
Phase 4 • Sponsor: Pavly Maged Jimmy Fouad • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Video footage may help doctors decide clubfoot treatment
Knowledge-focused CompletedDetermine the relationship between the PBS-score and treatment recommendations provided by senior pediatric orthopedic surgeons.
Sponsor: Region Stockholm • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:08 UTC
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Stanford study pits HIIT against moderate exercise to see which is healthier
Knowledge-focused OngoingThe purpose of this study is to compare the impact of high-intensity interval training (HIIT) versus moderate-intensity continuous training (MICT) on human health outcomes in healthy sedentary subjects, over 12 weeks of exercise training. The investigators will compare several h…
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Could skipping a needle stick make hemorrhoid treatment easier?
Symptom relief CompletedHaemorrhoidal disease is a common and benign condition (1). Anatomically, there is an external and internal component. Only internal haemorrhoidal disease is managed by radiofrequency. Different levels of severity of internal haemorrhoidal disease have been defined by the Golighe…
Phase 4 • Sponsor: Centre Hospitalier Departemental Vendee • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC