Laser vs scalpel: which biopsy hurts less for mouth disease?

NCT ID NCT07414797

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether using a laser for oral biopsies causes less pain and heals better than the standard punch scalpel in people with oral lichen planus. 112 adults were randomly assigned to one of the two methods. Researchers measured wound healing and discomfort after the procedure to see if the laser is a good alternative.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If laser biopsy proves better or equal, it could become the preferred method for diagnosing oral lichen planus, reducing patient discomfort.
What could go wrong
This is a small, single-center study comparing two procedures, not a treatment. Results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fondazione Policlinico Universitario A. Gemelli

    Roma, RM, 00168, Italy

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