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127005 trials found · Page 5197 of 6351
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Can a simple switch in how acetaminophen is given prevent delirium after hip surgery?
Symptom relief Recruiting nowThe INTACT-HIP trial study will evaluate feasibility of conducting a randomized, double-blinded controlled trial comparing postoperative treatment with intravenous (IV) acetaminophen versus oral acetaminophen, in older adults undergoing hip fracture surgery. The results of this …
Phase 4 • Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Jul 25, 2026 00:00 UTC
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New injection shows promise for smoothing frown lines and Crow's feet
Symptom relief CompletedThis study to assess aesthetic improvement following treatment with QM1114-DP.
Phase 3 • Sponsor: Galderma R&D • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Lullabies for epilepsy: a musical stress relief for expectant moms
Symptom relief Recruiting nowThis study's proposed intervention is the randomized participation of pregnant individuals with epilepsy in the Lullaby Project coordinated by a musical institution in Toronto. The purpose of this present study is to investigate the potential benefits of the Lullaby Project on pr…
Sponsor: University Health Network, Toronto • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Light-Based brain cap could replace radiation scans for kids
Knowledge-focused CompletedBackground: Neurocognitive disorders affect how the brain uses oxygen. They may affect mental development in children. These disorders can be studied with imaging scans that use radiation; however, these methods are not ideal for research on children. Two technologies-functional…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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Early allergy pill may stop sneezing before it starts
Symptom relief CompletedThis study is a proof-of-concept study to demonstrate if a daily dose of a 2-days pre-treatment of Fexofenadine 180mg is effective in alleviating the AR symptoms and to assess the additional benefit to the patient in terms of preventing Allergic Rhinitis (AR) symptoms. The total…
Phase 3 • Sponsor: Opella Healthcare Group SAS, a Sanofi Company • Aim: Symptom relief
Last updated Jun 26, 2026 15:14 UTC
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New nail for broken hips shows promise in healing
Disease control CompletedThis is a multicenter, prospective, Post-market Clinical Follow-up (PMCF) Study on the ZNN Bactiguard Cephalomedullary Nails. The objective of this study is to collect data confirming the safety, performance, and clinical benefit of the study device and instrumentation when used …
Sponsor: Zimmer Biomet • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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8 weeks of exercise reshapes heart risk in couch-potato women
Knowledge-focused CompletedThis randomized controlled trial investigated the effects of aerobic and resistance exercise on cardiovascular and inflammatory biomarkers in sedentary young women. Forty-five healthy sedentary females aged 18 to 25 years were randomly assigned to aerobic exercise, resistance exe…
Sponsor: Ondokuz Mayıs University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New study tests whether education and support groups ease bladder Cancer's hidden toll
Symptom relief Recruiting nowThis research is being done to learn more about coping and survivorship of women with bladder cancer, specifically regarding psychosocial distress and sexual dysfunction. This study is a non-therapeutic study and will randomize participants to a standard of care group and educati…
Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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New Alzheimer's drug OLX-07010 enters first human safety trial
Disease control OngoingThis First-in-human (FIH) study will evaluate the safety, tolerability, and pharmacokinetics of the tau self-association inhibitor, OLX-07010 in single ascending doses (SAD) and multiple ascending doses (MAD) in healthy adults (18-50 of age inclusive), and single dose in healthy …
Phase 1 • Sponsor: Oligomerix, Inc • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Wearable sensors shed light on movement in brittle bone disease
Knowledge-focused Completedinterventional pilot study with the enrollment of patients affected by Osteogenesis Imperfecta
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Spinal fracture patients: did integrative korean medicine help? new study looks back at real-world results
Knowledge-focused CompletedThe purpose of this study is to reveal the effectiveness and safety of integrative Korean medicine for Vertebral Compression Fracture in-patients by observing inpatients treated with integrative Korean medicine. This study is a retrospective observational study. The subjects for…
Sponsor: Jaseng Medical Foundation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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New program aims to boost cancer care quality in rural areas
Knowledge-focused OngoingThe purpose of this study is to implement and evaluate the recently developed Iowa Cancer Affiliate Network (ICAN) intervention. The ICAN intervention will consist of members of the research team providing ongoing support to participating hospitals in achieving the quality stand…
Sponsor: Mary Charlton • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC
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Sinus infection linked to fewer eye needles for AMD patients
Knowledge-focused Recruiting nowAn inflammatory component associated with AMD has been highlighted by genetic associations of predisposition to AMD, as well as by the recently demonstrated link between AMD and periodontitis. Some patients followed at the Fondation Adolphe de Rothschild Hospital for wet AMD see…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Timing delivery for gestational diabetes: What's the safest week?
Knowledge-focused Stopped earlyThis study will conduct a randomized trial among women with gestational diabetes (GDM). Study of Pregnancy And Neonatal health (SPAN), TIMing of dElivery (TIME) is a randomized trial that will recruit up to 3,450 pregnant women with uncontrolled GDM and randomize the timing of th…
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Scientists scan brains to uncover hidden links between movement and mood in rare disorder
Knowledge-focused CompletedBackground: Myoclonus dystonia (DYT-SGCE) is characterized by myoclonus and dystonia. Such condition is associated with a high prevalence of psychiatric symptoms which are part of the phenotype. The mechanisms underlying these non-motor symptoms are still poorly understood. Obj…
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Can a simple scan reveal hidden heart harm from cancer radiation?
Knowledge-focused Recruiting nowThis clinical trial examines positron emission tomography (PET)/computed tomography (CT) in evaluating cardiac radiation damage in patients with lung or esophageal cancer. As part of the treatment for lung or esophageal cancer, patients will undergo radiation therapy. Sometimes, …
Sponsor: Thomas Jefferson University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Can special exercises fix posture in girls? new study says maybe.
Knowledge-focused CompletedThe primary assumption of this study is to evaluate the impact of individual and group corrective therapy on changes in body posture in the transverse plane in girls aged 8-11 years diagnosed with posture disorders. The aim of the study is to assess the effectiveness of a 6-month…
Sponsor: Wioleta Chwalewska • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Could eccentric exercise be the key to stronger hearts?
Symptom relief Recruiting nowThe goal of this interventional study is to assess the training effects in a training schedule in which eccentric overload training and eccentric cycle training are used. Researchers will compare a training program of eccentric overload training and eccentric cycling training wi…
Sponsor: University Hospital, Antwerp • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Online modules may boost voice therapy success
Knowledge-focused CompletedThe purpose of this study is to assess the effects of incorporating educational online modules into voice therapy. One of the main reasons that voice therapy fails is lack of participation and engagement from the patient's side. The researchers hope to learn if increasing patient…
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Stomach-Suturing procedure shows early promise for obesity
Disease control CompletedCross-over arm of the pilot study evaluating a treatment for obesity.
Sponsor: USGI Medical • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC