New wrinkle treatment shows promise in small study

NCT ID NCT05148000

First seen May 31, 2026 · Last updated Jun 23, 2026 · Updated 3 times

Summary

This study tested a new botulinum toxin product called QM1114-DP in 25 adults with moderate to severe frown lines and crow's feet. Participants received one treatment and were asked to rate the change in their appearance. Most reported at least some improvement. The study is complete, but larger trials are needed to confirm these results.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Galderma Research Site

    New York, New York, 10021, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

QM1114-DP (a botulinum toxin type A product)

What this could lead to

If it works, this could offer a new option for temporarily reducing frown lines and crow's feet.

What could go wrong

This is a small, completed Phase 3 study with only 25 participants. Results may not apply to everyone, and risks include allergic reactions or temporary muscle weakness.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.