Botox breakthrough? study tests if injection depth matters for wrinkle treatment
NCT ID NCT05766683
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares injecting Botox at two different depths (2mm vs 4mm) to treat frown lines between the eyebrows. Twenty adults will receive a one-time treatment, and researchers will measure how well each depth reduces wrinkles and any side effects. The goal is to find the optimal injection depth for best results with minimal risks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
onabotulinumtoxinA (Botox)
What this could lead to
If it works, this could help doctors choose the best injection depth for treating frown lines with Botox, possibly improving results and reducing side effects.
What could go wrong
This is a very small, early-phase trial with only 20 people. The results may not apply to everyone, and the difference between depths might be small or not meaningful.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GLABELLAR FROWN LINES are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Henry Ford Health System
Detroit, Michigan, 48202, United States