Light-Based brain cap could replace radiation scans for kids
NCT ID NCT05642221
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether two light-based technologies, fNIRS and DCS, can safely measure brain activity in children with rare neurocognitive disorders like Niemann-Pick disease and Smith-Lemli-Opitz syndrome. 73 participants, including healthy volunteers, wore a cap with lights and sensors while doing computer tasks. The goal was to see if these scans are practical and safe, not to treat any condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could provide a safer, radiation-free way to study brain activity in children with neurocognitive disorders.
- What could go wrong
- This is a small pilot study (73 participants) focused on feasibility, not treatment. It may not show clear differences between groups or lead to clinical use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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