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116076 trials found · Page 5104 of 5804
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New tool could help kids with allergies breathe easier
Knowledge-focused Recruiting nowAllergic rhinitis is a common condition that affects adults as well as children and adolescents, often with impaired quality of life. Patients often report a poor level of satisfaction with the effectiveness of their treatment and are always looking for more drug combinations to …
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Massive cancer study aims to unlock tumor secrets and speed up trials
Knowledge-focused Recruiting nowSPECTA is a quality assured platform for collecting clinicopathologically annotated biological material, imaging data, operative images, environmental assessment, questionnaires as well as patient-reported outcomes from cancer patients to support biospecimen-based translational r…
Sponsor: European Organisation for Research and Treatment of Cancer - EORTC • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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New One-Hour blood test could speed up heart attack diagnosis
Diagnosis CompletedPredictable values of the 1-hour algorithm for estimating the concentration of troponin using highly sensitive reagents are 98-100% for excluding myocardial infarction (MI) and 75-80% for identifying this pathology. Such algorithms are developed for the rapid confirmation or excl…
Phase: NA • Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences • Aim: Diagnosis
Last updated Jun 28, 2026 00:00 UTC
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Which surgery for appendicitis has fewer complications?
Disease control Completedthis study compare between open and laparoscopic appendectomy
Phase: NA • Sponsor: Zagazig University • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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Can Oxygen-Sensing MRI help personalize childhood cancer treatment?
Knowledge-focused ENROLLING_BY_INVITATIONThis study will test the feasibility of using novel/existing imaging technologies focused on hypoxia measurements to determine "response to therapy" in pediatric soft tissue sarcomas as a pilot study. Specifically, the investigators will compare the sensitivity of Blood Oxygen Le…
Phase: PHASE1 • Sponsor: The Hospital for Sick Children • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Blood clot markers may predict severe pancreatitis
Knowledge-focused CompletedThe study aims to investigate pathophysiological changes in coagulation in relation to inflammation in patients with acute pancreatitis. Serum and plasma is sampled repeated days from admission. Analysis will be done after recruitment. Specific biomarkers accuracy for prediction …
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Brain wave monitor may spot dialysis danger
Diagnosis Recruiting nowThe severity of minimal dialysis disequilibrium syndrome (DDS) is currently detected and graded clinically using clinical criteria. Bispectral Index (BIS), an electroencephalographic (EEG) derived parameter is widely used in anesthesia and Critical Care setting to detect effects …
Sponsor: Suez Canal University • Aim: Diagnosis
Last updated Jun 27, 2026 12:24 UTC
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Nalbuphine vs morphine: which painkiller wins for Post-Surgery relief?
Symptom relief Completedto compare the analgesia and side effect of nalbuphine and morphine for elective Laparoscopic myomectomy.
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Brain fog after hip or knee replacement: how common and how long?
Knowledge-focused OngoingPatients assume that cognitive performance rapidly returns to baseline after anesthesia and surgery. Several studies have shown that one week after major non-cardiac surgery about 27% of patients have postoperative cognitive dysfunction (POCD) and 10% of patients at 3 months. Ver…
Sponsor: Dr. Stephen Choi • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:02 UTC
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New database to track freezing therapy for prostate cancer
Knowledge-focused Recruiting nowThis will be a prospectively maintained research database. The purpose is to record baseline parameters and treatment outcomes following of Cryotherapy for ablation of clinically localized prostate cancer.
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Neck workouts may ease jaw pain, small study finds
Symptom relief CompletedThe purpose of this study is; to determine the efficacy of cervical stabilization exercises in the treatment of patients with temporomandibular joint disfunction
Phase: NA • Sponsor: Bahçeşehir University • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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COPD's hidden toll on the brain revealed
Knowledge-focused CompletedCOPD is the third leading cause of combined morbidity, disability, and mortality in the United States and is often associated with cognitive impairment. The goal of the proposed project is to examine novel pulmonary and vascular physiological mechanisms that contribute to structu…
Sponsor: Karin Hoth • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Scientists dive deep into immune mysteries of gut diseases to personalize care
Knowledge-focused ENROLLING_BY_INVITATIONThe goal of the Precision Diagnosis in Inflammatory Bowel Disease, Cellular Therapies, and Transplantation (PREDICT) trial is to apply a systems-biology approach to enable precision diagnostics for the key immunologic outcomes for patients with Inflammatory Bowel Disease, Cellula…
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Iodine study: should all pregnant women get supplements or only those who need them?
Prevention CompletedPregnant women who attend at our antenatal clinic will random to 2 groups. First will receive routine iodine supplementation. The other will receive iodinated pill or only iron supplementation base on their urine iodine status.
Phase: NA • Sponsor: Chiang Mai University • Aim: Prevention
Last updated Jun 27, 2026 11:02 UTC
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Massive database study aims to uncover hidden child abuse numbers
Knowledge-focused CompletedThe epidemiological data currently available on child abuse in France are very inadequate. They do not make it possible to know the number of child victims, nor the precise context and impact of this violence. Very often, the figures put forward are underestimated. Improving the …
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Texting your way to weight loss: NHS trial tests SMS support
Symptom relief CompletedThis study evaluates the efficacy of a mobile telehealth short message service as a facilitator for weight management. Half of the participants will receive a standard care weight management group intervention, while the other half will receive daily text messages via their mobil…
Phase: NA • Sponsor: NHS Lothian • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Nearsighted patients studied for retinal detachment risk after cataract surgery
Knowledge-focused CompletedPhacoemulsification with implantation of posterior chamber lenses represents the gold standard of care for patients needing lens surgery, but there is an increased risk of developing pseudophakic retinal detachment after surgery. Especially myopic patients have an even higher ris…
Sponsor: Prim. Prof. Dr. Oliver Findl, MBA • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Eye-tracking study reveals how Alzheimer's disrupts everyday searching
Knowledge-focused CompletedThe aim is to understand which components of attentional deployment and selection are impaired in AD during searching in realistic scenes on a computer screen (Experiment 1) and in a natural setting (Experiment 2).The investigators will also examine how deficits in visual explora…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Brain zaps and imagination: a new way to boost motor learning in seniors?
Knowledge-focused CompletedThe mental repetition of movements - or motor imagery (MI) practice - facilitates motor learning. It allows avoiding fatigue that occurs during physical practice; this method is thus particularly interesting for elderly people. Transcranial direct current stimulation (tDCS) is a …
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:07 UTC
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New MRI dye could reveal hidden brain artery inflammation
Knowledge-focused CompletedIntracranial atherosclerosis (ICAS) accounts for 10 to 40%, depending on ethnicity, of the 700,000 ischemic strokes in the United States every year. The annual rate of recurrent stroke in patients with optimally treated ICAS remains more than twice the average of other stroke eti…
Phase: PHASE1 • Sponsor: Yale University • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:41 UTC